scharge after coronary artery bypass grafting.
  Even without the use of an intraoral scanner, post-and-cores can be obtained by using a part-digital fabrication workflow that requires pattern modeling (direct, indirect, or impression); however, studies on the adaptation of computer-aided design and computer-aided manufacturing (CAD-CAM) composite resin post-and-cores in comparison with metal cast post-and-cores are sparse.
 
  The purpose of this invitro study was to analyze the adaptation of CAD-CAM composite resin post-and-cores fabricated through a part-digital fabrication workflow and to compare it with that of metal cast post-and-cores fabricated through conventional methods.
 
  Eight extracted human premolars were endodontically treated and prepared for custom post-and-cores. Metal cast post-and-cores were fabricated with Ni-Cr alloy (Fit Cast-Sb Plus; Talmax) and conventional resin pattern modeling methods directly in the root canal (conventional direct modeling) or indirectly in a stone cast (conventional indirect modeling). Composite resin post-andthe part-digital fabrication workflow of CAD-CAM composite resin post-and-cores provided adaptation parameters within a clinically acceptable range and is less time consuming.
 Metal post-and-cores had slightly better adaptation than the CAD-CAM composite resin post-and-cores; however, the part-digital fabrication workflow of CAD-CAM composite resin post-and-cores provided adaptation parameters within a clinically acceptable range and is less time consuming.In this paper, the cascade control (CC), a structure popular among practitioners in many industry sectors, is used to bridge the two prominent research methodologies in SMC and ADRC for the purpose of multi-axis motion synchronization. In particular, the cascade sliding mode control(C-SMC) is first proposed, from which the cascade active disturbance rejection control (C-ADRC) is derived. This allows the linear and fal-function based nonlinear control actions to be naturally integrated and the controller parameters can be tuned easily with the proposed space-time scaling method.  https://www.selleckchem.com/products/ipi-549.html  The control law is constructed and validated in multi-axis motion synchronization of parallel mechanisms. The results show that the proposed scheme is effective and practical, with the robustness associated with the bandwidth constraints.In this paper, to reduce the computational and communication burden, the event-triggered distributed zero-sum differential game problem for multi-agent systems is investigated. Firstly, based on the Minimax principle, an adaptive event-triggered distributed iterative differential game strategy is derived with an adaptive triggering condition for updating the control scheme aperiodically. Then, to implement this proposed strategy, the solution of coupled Hamilton-Jacobi-Isaacs (HJI) equation is approximated by constructing the critic neural network (NN). In order to further relax the restrictive persistent of excitation (PE) condition, a novel PE-free updating law is designed by using the experience replay method. Then, the distributed event-triggered nonlinear system is expressed as an impulsive dynamical system. After analyzing the stability, the developed strategy ensures the uniformly ultimately bounded (UUB) of all the closed-loop signals. Moreover, the minimal intersample time is proved to be lower bounded, which avoids the infamous Zeno behavior. Finally, the simulation results show that the number of controller update is reduced obviously, which saves the computational and communication resources.
  The relationship between patient expectations and clinical outcomes has recently been of increasing interest in the field of orthopaedics. The objective of this study was to evaluate the relationships between (1) patient pre-treatment expectations and post-treatment clinical outcomes, and (2) fulfillment of expectations and patient satisfaction, following distal radius fracture.
 
  This was a prospective multicenter cohort study conducted across three hospitals. A total of 133 patients admitted to hospital between 2016 and 2018 with a distal radius fracture were recruited. Patients were administered the Trauma Expectation Factor (TEF) at baseline to measure expectations of pain and functioning at one-year post-injury. Patients were followed up at 6 and 12 months post-injury and outcomes were measured using the Trauma Outcome Measure (TOM), Shortened Disabilities of the Arm, Shoulder and Hand (QuickDASH) questionnaire, and Short-Form 12-item (SF-12) health survey. Fulfillment of expectations was measured as Trelevant to future clinical practice and research to best quantify and optimize patient outcomes.
 Patient expectations independently predicted outcomes at 6 and 12 months post-injury. Standardized assessment and management of patient expectations may be relevant to future clinical practice and research to best quantify and optimize patient outcomes.
  As the novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has emerged as a viral pandemic, data on the clinical characteristics and outcomes of patients with SARS-CoV-2 infection undergoing solid organ transplant are emerging. The objective of this systematic review was to assess currently published literature relating to the management, clinical course, and outcome of SARS-CoV-2 infection in liver, kidney, and heart solid organ transplant recipients.
 
  We conducted a systematic review to assess currently published literature relating to the management, clinical course, and outcome of SARS-CoV-2 infection in liver, kidney, and heart solid organ transplant recipients. Articles published through June 2020 were searched in the MEDLINE, ClinicalTrials.gov, and PubMed databases. We identified 49 eligible studies comprising a total of 403 solid organ transplant recipients.
 
  Older age, male sex, and preexisting comorbidities, including hypertension and/or diabetes, were the most common prevailing characteristics among the solid organ transplant recipients. Clinical presentation ranged from mild to severe disease, including multiorgan failure and death. We found an overall mortality rate of 21%.
 
  Our analysis suggests no increase in overall mortality or worse outcome in solid organ transplant recipients receiving immunosuppressive therapy compared with mortality in the general surgical population with SARS-CoV-2. Our findings suggest that transplant surgery and its immunosuppressive effects should not be a deterrent to proper surgical care for patients in the SARS-CoV-2 era.
 Our analysis suggests no increase in overall mortality or worse outcome in solid organ transplant recipients receiving immunosuppressive therapy compared with mortality in the general surgical population with SARS-CoV-2. Our findings suggest that transplant surgery and its immunosuppressive effects should not be a deterrent to proper surgical care for patients in the SARS-CoV-2 era.