https://www.selleckchem.com/products/act001-dmamcl.html The current outbreak of the Desert Locust has affected much of eastern Africa and has reached as far as Pakistan and India in Asia, generating significant agricultural losses in a region that is already highly unstable economically, politically, and in terms of food security for its human populations (FAO, 2020). Desert Locust outbreaks require a combination of weather, soil and vegetation conditions that favour the reproduction and aggregation of otherwise solitary individuals (Despland et al., 2000) (Figure 1a). When those conditions appear, locusts aggregate, multiply in large numbers and migrate long distances, turning into a plague and devastating crops on their way. This article is protected by copyright. All rights reserved.BACKGROUND Cover paroxysmal atrial fibrillation (pAF) is the most frequent cause of cardiac embolism. Our goal was to discover parameters associated with early pAF detection with intensive cardiac monitoring. METHODS Crypto-AF was a multicenter prospective study (four Comprehensive Stroke Centers) to detect pAF in non-lacunar cryptogenic stroke continuously monitored within the first 28 days. We assessed stroke severity, infarct pattern, large vessel occlusion at baseline (LVO), EKG analysis, supraventricular extrasystolia in Holter, left atria volume index (LAVI) and BNP level. The percentage of pAF detection and pAF episodes lasting more than 5 hours were registered. RESULTS Out of 296 patients included 264 patients completed the monitoring period with 23.1% (61/264) of pAF detection. Patients with pAF were older OR 1.04 (95% CI 1.01-1.08); they had more hemorrhagic infarction OR 4.03 (95% CI 1.44-11.22), they were more likely to have LVO OR 4.29 (95% CI 2.31-7.97) (p 5 hours 29.6% (21/71) Vs. 8.3% (12/144) OR 4.62 (95% CI 2.11-10.08), (p less then 0.001). In mean follow up of 26.82 months (SD 10.15) the stroke recurrence rate was 4.6% (12/260). CONCLUSIONS LVO in cryptogenic stroke