https://www.selleckchem.com/products/CP-690550.html l OA progression. The aim of this study was to evaluate the length and elasticity of the patellar tendon after open-wedge high tibial osteotomy (OWHTO). This case-controlled, analytical study included patients who underwent unilateral OWHTO operation and a control group. The length, thickness, strain elastography, and strain ratio of the patellar tendon were measured. The outcome measures were the Insall-Salvati Index (ISI), Blackburne-Peel Index (BPI), Caton Index (CI), the International Knee Documentation Committee Score (IKDC), Oxford Knee Score (OKS) and Knee Injury and Osteoarthritis Outcome Score (KOOS), Ahlbäck classification, and mechanical axis. Elasticity of the patellar tendon obtained by strain elastography were graded as follows; hardest or hard tissue, intermediate tissue, and soft tissue. The patellar tendon length was significantly shorter and patellar tendon thickness was significantly greater on the operated side compared with the values of the non-operated side and the control group (P<0.001 for all). Intermediate tissue was the most common elasticity grade (77%) for strain elastography on the operated side. Hardest tissue was the most common elasticity grade on the non-operated side of the patients (49.1%) and of the control group (70.0%). Patellar tendon length was correlated positively with IKDC, OKS, and KOOS values and patellar tendon thickness and strain ratio were correlated negatively with IKDC, OKS, and KOOS values. The patellar tendon seems to be shortened and thickened, with reduced stiffness after OWHTO. The ultrasound parameters are also associated with functional outcomes. The patellar tendon seems to be shortened and thickened, with reduced stiffness after OWHTO. The ultrasound parameters are also associated with functional outcomes. Prior literature suggests that opioid use prior to primary arthroplasty procedures results in increased risk for complication. Despite this, it is unk