https://www.selleckchem.com/products/stattic.html BACKGROUND Enterobiliary anastomoses are the main source of complications after liver transplantation. An endoscopic approach combining device-assisted enteroscopy and ERCP (DAE-ERCP) is technically feasible in post-surgical anatomy. AIMS This study aimed at assessing the efficacy, feasibility and safety of DAE-ERCP in liver transplanted patients (LT) and other subsets (non-LT). METHODS A systematic review and meta-analysis of studies involving DAE procedures in LT patients (between January 2000 and May 2017) was conducted. The main endpoints were endoscopic, diagnostic, therapeutic and overall success rates, complications and the need for surgery. RESULTS A total of 155 studies were retrieved, 6 relevant trials analyzed. Overall, 132 subjects (72 LT and 60 non-LT) undergoing 257 DAE-ERCP (135 and 122) were included. Complications were rare (4/257), no deaths occurred. These are the pooled success rates among LT and non-LT patients 80%-100% and 82%-95% (enteroscopic), 75%-100% and 89%-100% (diagnostic), 67%-100% and 92%-100% (therapeutic), 60%-100% and 79%-83% (overall results). The requirement for surgery was similar in the two subgroups. CONCLUSION In managing biliary complications the high diagnostic and therapeutic success rates of DAE-ERCP combined with its safety and feasibility encourages its application as a first-line approach to transplanted patients. This article is protected by copyright. All rights reserved.BACKGROUND Approximately 40% of women and 30% of men describe sexual dysfunction, although recognition in medical settings is suboptimal, due to problems in reporting and eliciting concerns relating to sexual function and satisfaction. Screening questionnaires may help to support this aspect of clinical practice. The Arizona sexual experiences scale (ASEX) includes items that quantify sex drive, arousal, vaginal lubrication or penile erection, ability to reach orgasm, and satisfaction from orgasm. MET