https://www.selleckchem.com/products/mk-8353-sch900353.html The results demonstrate how applying 2D-IR screening methodologies to spores would enable the creation of a library of spectra for classification purposes.Spectroscopic analysis, density functional theory (DFT) studies and surface enhanced Raman scattering (SERS) of antimycobactetial 4-[3-(4-acetylphenyl)ureido]-2-hydroxybenzoic acid (AUHB) have been studied on different silver sols. For Raman and SERS wavenumbers, very large changes are observed. Observed variations in the modes of ring may be due to surface π-electron interactions and presence of this indicated that poly substituted ring is more inclined than para substituted phenyl ring and assumes a inclined position for concentration 10-3 M. Changes in orientation are seen in SERS spectra depending on concentration. In order to find electron-rich and poor sites of AUHB, molecular electrostatic potential was also constructed. The molecular docking results show that binding affinity and interactions with the receptor DprE1 may be supporting evidence for further studies in design further AUHB pharmaceutical applications. Based on antitubercular activity of 4-aminosalicylic acid (PAS) and urea derivatives we designed, synthesized and investigated mutual PAS-urea derivatives as potential antimycobacterial agents.Dummy molecular imprinted polymers (MIPs) with carbendazim as a dummy template coated with Ag microspheres were fabricated in N, N-dimethylformamide solution via a surface-enhanced Raman scattering (SERS) enhancement for detection of benzimidazole by using methylacrylamide and ethylene glycol dimethacrylate as the functional monomer and cross-linker, respectively. The scanning electron microscope, transmission electron microscope, energy dispersive spectrometer, particle size distribution analysis, and X-ray diffraction were used to perform the morphology, size, and crystal structure for prepared Ag@dummy MIPs. Under the optimal conditions, the SERS