https://www.selleckchem.com/products/tegatrabetan.html The generation of different thermodynamically (meta)stable states is crucial for the development of smart solid-state luminescent materials. However, the design of luminophores with tunable aggregation states is remaining a grand challenge. Herein, we present a family of mechanochromic luminophores with tunable metastable states, based on the dynamically controllable π-π stacking of the flexible π-conjugated structure of 2,5-diarylamino-terephthalates in the solid state. The experimental data revealed that both the kinetically controlled metastable state and thermodynamic controlled stable state can be generated via tuning the intermolecular interactions such as π-π stacking and hydrogen bonds. As a result, the highly sensitive mechano-stimuli response of these luminophores was successfully achieved.Protected-area systems should conserve intraspecific genetic diversity. Because genetic data require resources to obtain, several approaches have been proposed for generating plans for protected-area systems (prioritizations) when genetic data are not available. Yet such surrogate-based approaches remain poorly tested. We evaluated the effectiveness of potential surrogate-based approaches based on microsatellite genetic data collected across the Iberian Peninsula for 7 amphibian and 3 reptilian species. Long-term environmental suitability did not effectively represent sites containing high genetic diversity (allelic richness). Prioritizations based on long-term environmental suitability had similar performance to random prioritizations. Geographic distances and resistance distances based on contemporary environmental suitability were not always effective surrogates for identification of combinations of sites that contain individuals with different genetic compositions. Our results demonstrate that population genetic data based on commonly used neutral markers can inform prioritizations, and we could not find an adequ