https://www.selleckchem.com/products/ro-61-8048.html Both exercises where performed with a knee flexion angle of 60˚ and the trunk positioned 40˚ (flexed trunk) and 60˚ (upright trunk) relative to the floor. Surface electrodes were used to collect EMG data. EMG activity of the gluteus maximus, gluteus medius, biceps femoris and rectus femoris was significantly greater with both single limb slide exercises as compared to both squat exercises. EMG activity was greater with the flexed trunk as compared to the upright trunk for the biceps femoris. Slider exercises produced a moderate or high level of activation for all muscles whereas all squat exercises produced a low-level activation. Level 3 Mechanism-based reasoning intervention study trial. Level 3 Mechanism-based reasoning intervention study trial. Anterior cruciate ligament injuries are among the most common knee injuries. Mechanism of injury is classified as contact or non-contact. The majority of anterior cruciate ligament ruptures occur through a non-contact mechanism of injury. Non-contact anterior cruciate ligament ruptures are associated with biomechanical and neuromuscular risk factors that can predispose athletes to injuries and may impact future function. Non-contact mechanism of injury may be preceded by poor dynamic knee stability and therefore those with a non-contact mechanism of injury may be prone to poor dynamic knee stability post-operatively. Understanding how mechanism of injury affects post-operative functional recovery may have clinical implications on rehabilitation. The purpose of this study was to determine if mechanism of injury influenced strength, functional performance, patient-reported outcome measures, and psychological outlook in athletes at four time points in the first two years following anterior cruciate ligament reconstruction. Secondary analysis of a clinical trial. Seventy-nine athletes underwent functional testing at enrollment after impairment resolution. Quadriceps strengt