https://www.selleckchem.com/ 1 mV and 31 nA after 12 weeks. The electrical performance of the self-powered pacemaker in this study is based on piezoelectric energy collection technology. The implanted piezoelectric vibration energy collector drives the pacemaker to generate electrical pulses, which directly stimulates the myocardial tissue through the epicardium to achieve the pacing effect. These results evidence the feasibility of the in-situ epicardial pacing strategy. This research will promote the design and development of self-powered cardiac pacemakers. These results evidence the feasibility of the in-situ epicardial pacing strategy. This research will promote the design and development of self-powered cardiac pacemakers. At present, the role of lncRNAs in the pathogenesis of hypoxia-induced pulmonary hypertension (HPH) is not fully understood. This study aimed to explore differences in the hypoxia-induced expression of lncRNAs and their potential role in multiple pulmonary artery cells. LncRNA expression in pulmonary artery smooth muscle cells (PASMCs), pulmonary microvascular endothelial cells (PMECs), and pericytes (PCs) was analyzed by high-throughput sequencing and compared between normoxic and hypoxic cells. Bioinformatics analysis was conducted to predict their functions. PASMCs, PMECs, and PCs displayed 275 (140 upregulated), 251 (162 upregulated), and 290 (176 upregulated) different lncRNAs, respectively. Among these, lncRNA TUG1 levels increased in PASMCs and PCs but decreased in PMECs. Bioinformatics analysis indicated that lncRNA TUG1 might target miR-145-5p, thereby affecting SOX4 and BMF expression, and could also regulate miR-129-5p levels to affect CYP1B1 and VCP expression. It could also regulate miR-138-5p levels to affect KCNK3 and RHOC expression. Hypoxia exposure of vascular cells resulted in differential expression of lncRNAs, especially lncRNA TUG1, which showed significant abnormal expression in all three types of vascular cells under