https://www.selleckchem.com/products/SL327.html 27, p<0.001). Multivariate regression analysis of CKD with variables in the hypertensive study group showed an association between CKD and sex (p=0.020), serum triglycerides (p=0.030) as well as serum uric acid (p=0.030). In the control group there was significant association between CKD and sex (p=0.020), serum total cholesterol (p=0.030) as well as serum uric acid (p=0.030). The prevalence of CKD among newly diagnosed hypertensives in southeast Nigeria was high. In this group, CKD had an association with sex, serum uric acid and serum triglyceride. The prevalence of CKD among newly diagnosed hypertensives in southeast Nigeria was high. In this group, CKD had an association with sex, serum uric acid and serum triglyceride. The multiple true or false (MTF) options with different negative scoring schemes and the Single Best of Five Answer (SBOFA) option of multiple choice questions are used in assessing knowledge in medical schools in Nigeria. There are diverse reasons for specific institutions to use a given scheme. These include large candidates' population, time pressure on those conducting the examination and limited resources. This study was set out to compare the performance of two negative scoring schemes of the MTF pattern of objective questions with the SBOFA pattern as the standard objective questions pattern in a medical school Methodology In this cross-sectional comparative study, selected response items were administered to medical students. A set comprised of SBOFA options (taken here as A-score) and the other two, MTF options with different negative marking schemes; negative marking (-1/2) as B-score, and negative marking (-1) as C-score. The mean scores were compared among the three schemes. Cutoff or pass mark enalty and the SBOFA scheme were more closely related than the MTF with -1 as penalty and SBOFA option. The SBOFA option had better correlation with the MTF with -1 as penalty while the -1/2 penal