https://www.selleckchem.com/products/epacadostat-incb024360.html Herein, a uniform spherical shaped Gd(III) doped Yb2O3 (Gd@Yb2O3) nanoparticles (NPs) was successfully synthesized via hydrothermal method for electrochemical detection of H2O2. The calcination effect and porosity of the materials well elaborated in the present work. The optical properties, size, morphological, thermal, sensing, surface and crystalline properties of synthesized materials were examined by several techniques. The enhanced electrocatalytic performance of Gd@Yb2O3 make the present sensor excellent towards the determination of H2O2.The anodic and cathodic peak current increased regularly with addition of H2O2 solution. The electrode coating surface was stable even after a number of electrochemical cycles and have high limit of detection (51 nM). Moreover, the present sensor was successfully employed for detection of H2O2 in real samples.Cynarin is one of the biologically active functional components present a wide range of pharmacological applications. Herein, we reported the fabrication and surface properties investigation of a new highly sensitive electrochemical sensor for the detection of cynarin. The electrochemical sensors were fabricated in several steps; the first being the synthesis of bi-thiophene derivatives-based monomers 3,3'-bithiophen (M1); 2-methoxy-5-carbaldehyde-[3,3'-bithiophene] (M2) and 2-((2-methoxy-[3,3'-bithiophen]-5-yl)methylene)malononitrile) (M3) followed by electrochemical polymerization on a glassy carbon electrode after which multi-walled carbon nanotube (MWCNT) and gold nanoparticles (GNP's) were electrodeposited layer-by-layer on the polymer coating to obtain multilayer electrochemical sensors. The morphological properties of the formed polymers were evaluated using SEM analysis and the apparent contact angles to preview the changes in surface properties after the functionalization of monomers and therefore their effects on the detection of cynarin. Analytica