001), while patients with an extreme age (i.e., group III) are more susceptible to blunt injury ( p  = 0.001). The MESS has a significant correlation to both age groups I and II ( p  = 0.001). Vein patch angioplasty and end-to-end primary repair should be adopted as the main treatment options for the repair of extremity vascular injuries in children. Moreover, other treatment modalities, such as repair with autologous vein graft/bypass surgery, may be adopted whenever possible. They are cost-effective, reliable, and simple techniques with fewer postoperative complication, especially in poor/limited resources.Little is known about the surgical challenges and outcomes of kidney transplantation (KT) in the face of severe iliac occlusive disease (IOD). We aim to examine our institution's experience and outcomes compared with all KT patients. Retrospective review of our multi-institutional transplant database identified patients with IOD requiring vascular surgery involvement for iliac artery endarterectomy at time of KT from 2000 to 2018. Clinical data, imaging studies, and surgical outcomes of 22 consecutive patients were reviewed. Our primary end-point was allograft survival. Secondary end-points included mortality and perioperative complications. A total of 6,757 KT were performed at our three sites (Florida, Arizona, and Minnesota); there were 22 (0.32%) patients receiving a KT with concomitant IOD requiring iliac artery endarterectomy. Mean patient age was 61.45 ± 7 years. There were 13 (59.1%) male patients. The most common etiology of renal failure was diabetic nephropathy in 10 patients (45.5%) followed by a phrectomy. IOD patients selected for KT are not common and although challenging, they have similar outcomes to our standard KT patients. The 1- and 3-year allograft survivals were 90.1 and 86.4% versus 96.0 and 90.3% in the general KT patient population. With these excellent outcomes, we recommend expanding the criteria for KT to include patients with IOD with prior vascular surgery consultation to prevent progression of IOD or prevention of wait list removal in select patients who are otherwise good candidates for KT.Plant genome editing, particularly CRISPR-Cas biotechnologies, has rapidly evolved and drawn enormous attention all around the world in the last decade. The cutting-edge technologies have had substantial impact on precise genome editing for manipulating gene expression, stacking gene mutations, and improving crop agronomic traits. Following the global trends, investigations on CRISPR-Cas have been thriving in Australia, especially in agriculture sciences. Importantly, CRISPR-edited plants, classified as SDN-1 organisms (SDN site-directed nuclease), have been given a green light in Australia, with regulatory bodies indicating they will not be classified as a genetically modified organism (GMO) if no foreign DNA is present in an edited plant. As a result, genome-edited products would not attract the onerous regulation required for the introduction of a GMO, which could mean more rapid deployment of new varieties and products that could be traded freely in Australia, and potentially to export markets. In the present review, we discuss the current status and prospects of plant genome editing in Australia by highlighting several species of interest. Using these species as case studies, we discuss the priorities and potential of plant genome editing, as well as the remaining challenges.Meta-analytical findings suggested a positive link between trait mindfulness and prosociality. However, most correlational studies on mindfulness and prosociality have relied on self-report measures. The present work aimed to address this serious limitation by investigating actual prosocial behavior. We further focused on mindfulness as a multi-dimensional personality trait to disentangle effects of different mindfulness aspects. In addition, we tested whether the relation between trait mindfulness and prosocial behavior emerges under a theoretical meaningful experimental boundary condition (i.e., feelings of guilt). In two studies (using four different samples; N = 1240), we did not find support for a positive link between trait mindfulness and (a) charitable donation and (b) behavior in an incentivized economic game, respectively. Evidence for manipulated guilt-level as a moderator was inconclusive. Taken together, the findings point to a more complex role of trait mindfulness for prosocial behavior. Limitations and ideas for further research are discussed.During the COVID-19 pandemic in early 2020, domestic violence, interpersonal conflicts, and cyberbullying have risen sharply in China. We speculate that the perceived threat of COVID-19 is related to a general, non-target-specific aggressive tendency during the pandemic. We surveyed 1556 Chinese people in April 2020 (757 people in Hubei Province, the pandemic epicenter in China, and 799 in other regions of China where the pandemic is relatively not severe).  https://www.selleckchem.com/products/asciminib-abl001.html  A multiple-group structural equation modeling analysis found significant total effects between perceived threat of COVID-19 and aggressive tendencies during the pandemic in both regional groups, and the effect between them was mainly achieved through the mediating roles of sense of control and powerlessness during the pandemic. For all participants, negative coping strategies significantly aggravated the association between perceived threat of COVID-19 and aggressive tendencies during the pandemic, but the buffers were different across regions of outbreak severity. For participants in other regions where the pandemic is relatively not severe, positive coping strategies could mitigate the association between perceived threat of COVID-19 and aggressions. However, for participants in Hubei Province, the epicenter of China's pandemic, higher life satisfaction was more effective in buffering. These findings extend the possible consequences of the perceived COVID-19 threat and suggest that improving the life satisfaction of residents in areas with severe outbreaks is more effective in mitigating the adverse effects of COVID-19.
  The online version contains supplementary material available at 10.1007/s12144-021-01792-7.
 The online version contains supplementary material available at 10.1007/s12144-021-01792-7.