https://www.selleckchem.com/products/epz015666.html Coronavirus disease 2019 (COVID-19) is a rapidly emerging pandemic disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Critical COVID-19 is thought to be associated with a hyper-inflammatory process that can develop into acute respiratory distress syndrome, a critical disease normally mediated by dysfunctional neutrophils. This study tested the hypothesis whether the neutrophil compartment displays characteristics of hyperinflammation in COVID-19 patients. Therefore, a prospective study was performed on all patients with suspected COVID-19 presenting at the emergency room of a large academic hospital. Blood drawn within 2 d after hospital presentation was analyzed by point-of-care automated flow cytometry and compared with blood samples collected at later time points. COVID-19 patients did not exhibit neutrophilia or eosinopenia. Unexpectedly neutrophil activation markers (CD11b, CD16, CD10, and CD62L) did not differ between COVID-19-positive patients and COVID-19-negative patients diagnosed with other bacterial/viral infections, or between COVID-19 severity groups. In all patients, a decrease was found in the neutrophil maturation markers indicating an inflammation-induced left shift of the neutrophil compartment. In COVID-19 this was associated with disease severity. The purpose of this study is to examine the relationship between keywords in existing global health nursing studies during 44years (1974-2017) and to develop schematic diagrams of the relationship between these keywords from a macro perspective. It is to identify the trend of the literature in global health nursing field. A descriptive bibliometric analysis of publications in global health nursing. The keywords from 7,115 articles and literatures were examined using the Text Rank Analyzer via the applied text network analysis with NetMiner 4.0. As for global health nursing, keywords with the most frequent appearance an