https://www.selleckchem.com/products/azd5153-6-hydroxy-2-naphthoic-acid.html  The aim of this study is to evaluate the color alteration and shore A hardness of a medical silicone with extrinsic pigmentation, before and after accelerated aging.  Twenty samples (Silastic Q7-4735) were made with an intrinsic pigmentation. This intrinsic pigmentation was composed of a pink pigment (H-109-P, Factor II) and an opacifier (ZnO). All samples had standardized dimensions (45-mm diameter and 2-mm thickness). Half of the 20 samples manufactured subsequently received an extrinsic pigment (Tan FE-215, Factor II). Therefore, two groups were created ( = 10) Group 1, group with intrinsic pigmentation and without extrinsic pigmentation (control) and Group 2, group with intrinsic and extrinsic pigmentation. Samples were submitted to color and Shore A hardness tests, before and after 1,008 hours of aging.  Color alteration data were submitted to Student's -test ( = 0.05). Shore A hardness data were submitted to two-way analysis of variance and Tukey test ( = 0.05).  The incorporation of the extrinsic pigment on the silicone did not affect its color (ΔE) when the two groups were compared ( = 0.232). Regarding the hardness test, the interaction between group and period did not interfere with the hardness results( =0.599). However, the period factor showed that there was a reduction in the hardness of the silicone after aging ( < 0.05).  In this study, all the hardness and color results of the silicone used were clinically acceptable, regardless of the presence of extrinsic pigmentation.  In this study, all the hardness and color results of the silicone used were clinically acceptable, regardless of the presence of extrinsic pigmentation. Bacterial exposure to stress, such as reduced water activity (aw), can increase thermal resistance. Pathogen thermal resistance studies on low-aw foods use a variety of methods to inoculate food, as well as strategies to reduce aw, which can influence obs