https://www.selleckchem.com/products/paeoniflorin.html Random-effects model meta-analysis revealed small positive tDCS effects on alcohol craving and consumption. Specifically, bilateral tDCS protocols significantly reduced alcohol craving, and further anodal tDCS on right dorsolateral prefrontal cortex (DLPFC) and cathodal tDCS on left DLPFC revealed significant positive effects. The multiple sessions of tDCS protocols showed better effects on reducing alcohol craving. The current findings suggested that bilateral tDCS protocols including anodal tDCS on right DLPFC and cathodal tDCS on left DLPFC with multiple sessions may effectively improve tDCS effects on symptoms of alcohol use disorder. The current findings suggested that bilateral tDCS protocols including anodal tDCS on right DLPFC and cathodal tDCS on left DLPFC with multiple sessions may effectively improve tDCS effects on symptoms of alcohol use disorder. It is known that viral infections are epidemiologically prevalent and some of them are harmful to the central nervous system (CNS) due to the development of neuropsychiatric syndromes which affect the cognitive, affective, behavioral and perceptual domains. To carry out a comprehensive analysis of the psychiatric and neuropsychiatric repercussions of COVID-19 based on epidemiological, pathophysiological and clinical foundations observed in previous and recent pandemic events, and also to make a proposition about effective therapeutic interventions to help tackle this serious public health problem, more specifically in its neuropsychiatric developments. This current literature review has utilized literature reserves and scientific search engines MEDLINE, EMBASE and Web of Science. The search terms included, "SARS-CoV-2", "etiology," "psychiatric and neuropsychiatric repercussions", "severe infections" "COVID-19". Specific choices of unique papers from each of the searches were identified. The inclusion cr necrosis and distressing pain.Sphingolipids are pot