https://www.selleckchem.com/products/pf-2545920.html In several deceased donor kidney allocation systems, organs from elderly donors are allocated primarily to elderly recipients. The Eurotransplant Senior Program (ESP) was implemented in 1999 and since then, especially in Europe, the use of organs from elderly donors has steadily increased. The proportion of ≥60-year-old donors reported to the Collaborative Transplant Study (CTS) by European centers has doubled, from 21% in 2000-2001 to 42% in 2016-2017. Therefore, in the era of organ shortage it is a matter of debate whether kidney organs from elderly donors should only be allocated to elderly recipients or whether less then 65-year-old recipients can also benefit from these generally as 'marginal' categorized organs. To discuss this issue, a European Consensus Meeting was organized by the CTS on April 12, 2018 in Heidelberg, in which 36 experts participated. Based on available evidence, it was unanimously concluded that kidney organs from 65-74-year-old donors can also be allocated to 55-64-year-old recipients, especially if these organs are from donors with no history of hypertension, no increased creatinine, no cerebrovascular death, and no other reason for defining a marginal donor, such as diabetes or cancer. This article is protected by copyright. All rights reserved.Altemeier's procedure is a well-known operation that can be performed under spinal anaesthesia, avoiding the trauma of a laparotomy, reducing the surgical stress and allowing a rapid recovery of patients[1]. Usually patients with full-thickness rectal prolapse are investigated before the elective surgery and undergo preoperative assessment starting with a clinical examination and then further investigations including pelvic MRI, dynamic defecography and anorectal manometry[2]. All contribute to the decision to carry out a safe and "standard" perineal rectosigmoidectomy. However, these cannot be performed as an emergency if the prolapse becomes s