https://www.selleckchem.com/btk.html We report the case of a 36-year-old health care worker who suffered a subacute infarct with a mild deviation of the midline, and a large vessel occlusion with a free-floating thrombus in the ascending aorta in the context of a SARS-CoV-2 infection. With this case we want to increase the awareness about severe forms of systemic ischemia and stroke in patients with signs of COVID infection. This article is protected by copyright. All rights reserved.OBJECTIVE The present case-control study aims to compare the psychological status of patients with and without halitosis, and investigate the association of psychological disorders and halitosis. METHODS Patients who complained about bad breath and diagnosed with genuine halitosis were assigned to the halitosis group, while patients without genuine halitosis were assigned into the control group (n=106, each group). Information on the demographics and Symptom Checklist-90 (SCL-90) of participants were collected. The organoleptic score and Halimeter measurement were used to measure halitosis. RESULTS The mean SCL-90 score of participants in the halitosis group (0.63) was significantly greater than that in the control group (0.48) (P=0.002). The scores of the domains of interpersonal sensitivity, anxiety, depression and paranoid ideation were found to be significantly different between two groups (P less then 0.05). However, there were no significant differences in SCL-90 scores between the mild and moderate-severe halitosis groups (P=0.479). CONCLUSION The psychological status of genuine halitosis patients was significantly worse compared to normal patients without halitosis complaint and also without halitosis. The main problems were in the aspects of interpersonal sensitivity, anxiety, depression and paranoia. However, the negative impact was not related with the severity of halitosis. This article is protected by copyright. All rights reserved.BACKGROUND Hyperglycemia in acute stroke l