CONCLUSION Implantation of the XtraFocus intraocular pinhole inside the capsular bag is safe. Improvement in both uncorrected and best-corrected visual acuity was significant and sustained overtime. ILO does not occur when this implant is positioned in the capsular bag together with a primary IOL.PURPOSE To develop a new method that makes it easy to detect accuracy deficiencies of any intraocular lens power calculation formulae and to test it on 9 different formulae. SETTING IOA, Madrid, Spain DESIGN Retrospective observational case series. METHODS This study's first stage included 3519 eyes from 3519 candidates to cataract surgery for which frequency distributions for the following biometric eye parameters were computed axial length (AXL), anterior-chamber depth (ACD), lens thickness (LT), white-to-white (WTW) and mean corneal radius (Rm). The resulting data for each parameter were 5, 25, 75 and 95 percentile, which allowed us to define the corresponding normality range. In a second stage, the new graphic-representation method was tested for 9 different formulae in a sample of 70 eyes undergoing cataract surgery with multifocal intraocular lens (MIOL) implantation. RESULTS Normality ranges (defined as the 25-to-75-percentile interval) were 22.84 to 24.42 mm for AXL, 2.86 to 3.39 mm for ACD, 4.36 to 4.88 mm for LT, 11.64 to 12.19 mm for WTW and 7.52 to 7.87 mm for Rm, with lower sizes in women. No significant differences were found along the 9 formulae for percentage of eyes in ±0.50D (p=0.82) or ±1.00D (p=0.97). The new graphical method showed less accuracy in ±0.50 D for ACDs from 2.46 to 2.85 mm (5 to 25 percentile) for several formulae (p less then 0.05). CONCLUSIONS 9 formulae showed non-significant differences in the general predictability for a sample of eyes candidates to MIOL implantation. Predictability in this sample decreased for short ACDs.INTRODUCTION Patient-reported pain scores and opioid use have not been quantified after outpatient adolescent anterior cruciate ligament reconstruction (ACLR). METHODS Patients aged 12 to 18 years undergoing primary isolated ACLR, with or without meniscal treatment, were prospectively recruited. Patients actively taking opioids or with previous extended use of opioids were excluded. Two orthopaedic surgeons performed ACLR and determined the use of a hamstring or bone-patellar tendon-bone autograft. For postoperative pain management, patients were prescribed 40 tablets of hydrocodone/acetaminophen 5/325 mg. Patients were instructed to document daily pill consumption and side effects through a daily log for 6 weeks. Patients completed the American Pain Society Patient Outcome Questionnaire at the end of weeks 1 and 6. RESULTS One hundred three patients were enrolled, with age 12.5 to 18.9 years (mean 16.2 y ± 1.3), weight 41.3 to 113.6 kg (mean 72.4 kg ± 17.2), and body mass index 17.8 to 40.1 (mean 25.9 ± 4.9)nce on pill consumption. LEVEL OF EVIDENCE Level IV, case series.BACKGROUND Therapeutic bronchoscopy (TB) is an accepted strategy for the symptomatic management of central airway malignant obstruction. Stent insertion is recommended in case of extrinsic compression, but its value in preventing airway re-obstruction after endobronchial treatment without extrinsic compression is unknown. OBJECTIVE Silicone stent Placement in symptomatic airway Obstruction due to non-small cell lung Cancer (SPOC) is the first randomized controlled trial investigating the potential benefit of silicone stent insertion after successful TB in symptomatic malignant airway obstruction without extrinsic compression. METHOD We planned an inclusion of 170 patients in each group (stent or no stent) over a period of 3 years with 1-year follow-up. The 1-year survival rate without symptomatic local recurrence was the main endpoint. Recurrence rate, survival, quality of life, and stent tolerance were secondary endpoints. During 1-year follow-up, clinical events were monitored by flexible bronchoscopies andneed for new TB. Stenting does not affect the quality of life and is suggested for patients after failure of first-line chemotherapy. It is not suggested in patients without previous oncologic treatment. © 2020 S. Karger AG, Basel.OBJECTIVE We aimed to investigate the relationships of body mass index (BMI), waist circumference (WC), and obesity defined using a combination of both indexes, with the incidence of hypertension in a Chinese community-based population. METHODS A total of 1,927 Chinese participants (57.2 ± 8.9 years old) with normal blood pressure at baseline were recruited from the Shijingshan community in Beijing. Incident hypertension was defined as blood pressure ≥140/90 mm Hg, self-reported hypertension, or the use of any antihypertensive medication at the follow-up visit. RESULTS During 2.3 years of follow-up, 19.1% (n = 97) of the men and 13.6% (n = 158) of the women developed incident hypertension. The adjusted odds ratios (ORs) (95% confidence intervals [CIs]) for obesity (BMI ≥30) were 3.49 (1.59-7.66) and 2.60 (1.48-4.55) for men and women, respectively. A 1-point increase in BMI was associated with 8% (OR = 1.08, 95% CI 1.00-1.17) and 10% (OR = 1.10, 95% CI 1.05-1.16) increases in the incidence of hypertension in men and women, respectively. Abdominal obesity (WC ≥90 cm in men and ≥85 cm in women) was positively associated with incident hypertension in both men (adjusted OR = 1.79, 95% CI 1.10-2.91) and women (adjusted OR = 1.61, 95% CI 1.09-2.40). A 1-cm increase in WC was associated with 4% (adjusted OR = 1.04, 95% CI 1.01-1.07) and 4% (adjusted OR = 1.04, 95% CI 1.02-1.07) increases in the incidence of hypertension in men and women, respectively. The combination of abnormal BMI and WC has the highest risk for hypertension in both men (adjusted OR = 3.10, 95% CI 1.48-6.50) and women (adjusted OR = 2.51, 95% CI 1.43-4.40). CONCLUSIONS This study shows that BMI, WC, and an index that combined the two are independently associated with incident hypertension in a Chinese community-based population. © 2020 The Author(s) Published by S. Karger AG, Basel.BACKGROUND Increasing life expectancy worldwide means more people will develop dementia. Despite the rapid growth in older Bangladeshi immigrants living in the UK, there is little evidence of how community members understand and view the process of ageing and dementia. However, Bangladeshis have a higher risk of developing type 2 diabetes and heart disease, both of which are important indicators of dementia development in old age.  https://www.selleckchem.com/peptide/box5.html  This study aimed to explore and analyse the perception and knowledge of, and attitudes towards, ageing and dementia among the Bangladeshi community. METHODS A qualitative research approach guided two separate focus group discussions held with Bangladeshi adults in Portsmouth, UK. A topic guide was used alongside two vignettes depicting either early- or late-stage dementia to stimulate discussion. The data were recorded, transcribed, and analysed thematically using NVivo qualitative software. RESULTS Three main themes emerged (1) knowledge and perceptions of dementia; (2) perceived causes of dementia; and (3) perceptions of stigma about dementia.