https://www.selleckchem.com/products/ctpi-2.html Improving our experimental and theoretical knowledge of electric potentials at liquid-solid boundaries is essential to achieve a deeper understanding of the driving forces behind interfacial processes. Electron holography has proved successful in probing solid-solid interfaces but requires knowledge of the materials' mean inner potential (MIP, V_0), which is a fundamental bulk material property. Combining off-axis electron holography with liquid phase transmission electron microscopy (LPTEM), we provide the first quantitative MIP determination of liquid water V_0=+4.48±0.19  V. This value is larger than most theoretical predictions, and to explain the disagreement we assess the dominant factors needed in quantum simulations of liquid water. A precise MIP lays the foundations for nanoscale holographic potential measurements in liquids, and provides a benchmark to improve quantum mechanical descriptions of aqueous systems and their interfaces in, e.g., electrochemistry, solvation processes, and spectroscopy.What is the fastest way to heat a system which is coupled to a temperature controlled oven? The intuitive answer is to use only the hottest temperature available. However, we show that often it is possible to achieve an exponentially faster heating protocol. Surprisingly, this protocol can have a precooling stage-cooling the system before heating it shortens the heating time significantly. To demonstrate such improvements in many-body systems, we developed a projection-based method with which such protocols can be found in large systems, as we demonstrate on the 2D antiferromagnet Ising model.The competitive conformation chirality of dynamically racemic water-soluble pillar[5]arene WP5 can be induced by 19 different l-amino acid ethyl ester hydrochlorides. Among them, l-Arg-OEt and 18 other l-amino acid ethyl ester hydrochlorides can induce the opposite-handedness conformation of WP5. This was ascribed to the differe