https://www.selleckchem.com/products/itacitinib-incb39110.html To determine the incidence of HIV acquisition in women postrape compared with a cohort of women who had not been raped. A prospective cohort study. The Rape Impact Cohort Evaluation study based in Durban, South Africa, enrolled women aged 16-40 years from postrape care services, and a control group of women from Primary Healthcare services. Women who were HIV negative at baseline (441 in the rape-exposed group and 578 in the control group) were followed for 12-36 months with assessments every 3 months in the first year and every 6 months thereafter. Multivariable Cox regression models adjusted for baseline and time varying covariates were used to investigate the effect of rape exposure on HIV incidence over follow-up. Eighty-six women acquired HIV during 1605.5 total person-years of follow-up, with an incident rate of 6.6 per 100 person-years [95% confidence interval (CI) 4.8-9.1] among the rape exposed group and 4.7 per 100 person-years (95% CI 3.5-6.2) among control group. After controlling for confounders (age, previous trauma, social support, perceived stress, multiple partners and transactional sex with a casual partner), women exposed to rape had a 60% increased risk of acquiring HIV [adjusted hazard ratio 1.59 (95% CI 1.01-2.48)] compared with those not exposed. Survival analysis showed difference in HIV incident occurred after month 9. Rape is a long-term risk factor for HIV acquisition. Rape survivors need both immediate and long-term HIV prevention and care. Rape is a long-term risk factor for HIV acquisition. Rape survivors need both immediate and long-term HIV prevention and care. High-quality training opportunities for providers in limited-resource settings are often scarce or nonexistent. This can lead to a dearth of boots-on-the-ground workers capable of translating knowledge into effective action. The tested telehealth education model of Project ECHO (Extension for Community Healthcare Ou