Two hundred ten (44.2%) out of four hundred seventy-five participants responded to Survey 2; 195 had completed hub shifts. Younger, female GPs predominated. Very high levels of infection control procedures were reported. Participants commented positively on teamworking, environment and systems. However, 'real-time' ambulance service data suggest the peak of the surge may have passed by the time the hubs were established.
 
  Academic departments, GPs and the Irish health system collaborated effectively to respond to the need for community assessment of COVID-19 patients.
 Academic departments, GPs and the Irish health system collaborated effectively to respond to the need for community assessment of COVID-19 patients.To investigate the reliability of newly defined CT-related parameters and cardiovascular risk factors in groups adjusted for stone size and location to predict spontaneous stone passage (SP) of uncomplicated ureteral stones ≤ 10 mm. The data of 280 adult patients with solitary unilateral ureteral stones ≤ 10 mm in diameter in non-contrast computed tomography were prospectively recorded. All patients undergoing a four-week observation protocol with medical expulsive therapy using tamsulosin were divided into two groups according to SP or no SP. Demographic, clinical and radiological findings of these groups were recorded. Spontaneous stone passage was observed in 176 (62.9%) of the patients, whereas the SP rate was 57.6% for 118 upper ureteral stones and 66.7% for 162 lower ureteral stones. The SP rate was 13.3 times greater with ureteral wall thickness  less then  1.88 mm, 4.4 times greater with a ratio of ureter to stone diameter of  less then  1.24, 3.4 times greater with Framingham score of  less then  11.5%, 2 times greater with neutrophil lymphocyte ratio  less then  1.96, 1.9 times greater with ureteral diameter  less then  6.33 mm and 1.5 times greater with stone volume  less then  38.54 mm3. Lower levels of ureteral wall thickness, ratio of ureter to stone diameter, Framingham score, neutrophil lymphocyte ratio, ureteral diameter, stone volume and absence of hydronephrosis were found to be more successful predictors. We consider that the success rate can be increased by selection of the proper option (observation or active treatment) according to these predictors.Shiny and screaming cowbirds are avian interspecific brood parasites that locate and prospect host nests in daylight and return from one to several days later to lay an egg during the pre-dawn twilight. Thus, during nest location and prospecting, both location information and visual features are available, but the latter become less salient in the low-light conditions when the nests are visited for laying. This raises the question of how these different sources of information interact, and whether this reflects different behavioural specializations across sexes. Differences are expected, because in shiny cowbirds, females act alone, but in screaming cowbirds, both sexes make exploratory and laying nest visits together. We trained females and males of shiny and screaming cowbird to locate a food source signalled by both colour and position (cues associated), and evaluated performance after displacing the colour cue to make it misleading (cues dissociated).  https://www.selleckchem.com/products/durvalumab.html  There were no sex or species differences in acquisition performance while the cues were associated. When the colour cue was relocated, individuals of both sexes and species located the food source making fewer visits to non-baited wells than expected by chance, indicating that they all retained the position as an informative cue. In this phase, however, shiny cowbird females, but not screaming, outperformed conspecific males, visiting fewer non-baited wells before finding the food location and making straighter paths in the search. These results are consistent with a greater reliance on spatial memory, as expected from the shiny cowbird female's specialization on nest location behaviour.Intracranial hemorrhage (ICH) occurs when a blood vessel ruptures in the brain. This leads to significant morbidity and mortality, the likelihood of which is predicated on the size of the bleeding event. X-ray computed tomography (CT) scans allow clinicians and researchers to qualitatively and quantitatively diagnose hemorrhagic stroke, guide interventions and determine inclusion criteria of patients in clinical trials. There is no currently available open source, validated tool to quickly segment hemorrhage. Using an automated pipeline and 2D and 3D deep neural networks, we show that we can quickly and accurately estimate ICH volume with high agreement with time-consuming manual segmentation. The training and validation datasets include significant heterogeneity in terms of pathology, such as the presence of intraventricular (IVH) or subdural hemorrhages (SDH) as well as variable image acquisition parameters. We show that deep neural networks trained with an appropriate anatomic context in the network receptor segmentation of ICH, the only model evaluated with the presence of both IVH and SDH and the only model validated in the workflow of a series of clinical trials.Household food insecurity is associated with youth behavioral problems, yet few studies have examined potential mechanisms that underline this association, particularly among adolescents. The Family Stress Model (FSM) states that food insecurity potentially impacts adolescent psychosocial adjustment indirectly through its effects on parental psychological functioning and parenting. The current study examined data from the Children, Welfare, and Families study (N = 687, 53% female, Mage of child at baseline = 11.74 years, SD = 1.39) to determine whether household food insecurity at the beginning of adolescence predicts later behavioral outcomes and whether that association is mediated through caregiver depression and caregiver-adolescent relationship quality. Caregivers completed measures of past-year household food insecurity, current self-reported depressive symptoms and adolescent behavior problems, while adolescents completed a measure of current caregiver-adolescent relationship quality. A serial multiple mediator model, controlling for baseline values of mediators, outcomes, and relevant demographic covariates, indicated a significant total indirect effect, whereas the total direct effect was not significant.