This article addresses the issue and practice of surrogacy in France. Surrogacy contracts are void under French law, and intermediaries, medical personnel, and in some cases, parents can be penalized if they partake in this method of ART. Consequently, the vast majority of French children born of surrogacy result from cross-border practices that their parents undertake. Divided into three parts, this chapter will first explore the French legal framework of surrogacy, then explore the cross-border practices at play and the difficulties they raise for ensuing parents and children once back on French soil, and finally examines diverse social movements and discourse either for or against the legalization of surrogacy in France. It concludes by arguing that before establishing a regulatory framework for surrogacy, the most pressing issue is to protect children born of French parents abroad via surrogacy once the family returns to the country.
  Mindfulness-Oriented Recovery Enhancement (MORE) is a mind-body therapy that unites complementary aspects of mindfulness training, third-wave cognitive behavioral therapy (CBT), and principles from positive psychology into an integrative treatment for addiction and its comorbidities. As interest in MORE has grown among researchers and clinicians, there is an increasing need to provide quality assurance measures to ensure treatment integrity during implementation of MORE. Here, we describe the development and validation of the Mindfulness-Oriented Recovery Enhancement Fidelity Measure (MORE-FM).
 
  We developed a 17-item scale assessing therapist competence and adherence to the MORE treatment manual, which was then used for fidelity monitoring of 40 MORE treatment sessions across two Stage 2 and two Stage 1 RCT for addictive behaviors (e.g., opioid misuse, obesity) involving a total N =295.
 
  Internal consistency for the Adherence (
  =.89) and Competence subscales (
  =.92) was high, and interrater reliability was adequate (Adherence subscale ICC=.77; Competence subscale ICC=.51), with therapists exhibiting good-to-excellent levels of fidelity across all trials.  https://www.selleckchem.com/products/rp-6685.html  Importantly, linear mixed modeling indicated that higher levels of overall fidelity were associated with greater reductions in opioid misuse across two Stage 2 RCTs (
  
  =7.38, 
  =.009), indicating that the MORE-FM is a valid measure of treatment fidelity that can predict clinical outcomes.
 
  Findings from this study yielded insights for future iterations of the MORE-FM. In sum, the MORE-FM is a valuable tool for assessing and enhancing the integrity of MORE in future research trials and clinical applications.
 Findings from this study yielded insights for future iterations of the MORE-FM. In sum, the MORE-FM is a valuable tool for assessing and enhancing the integrity of MORE in future research trials and clinical applications.Introduction Obesity is a public health problem that is associated with cerebrovascular diseases, such as ischemic stroke. The coexistence of obesity with cerebral ischemia has been suggested to be considerably detrimental to the neurological system. Objective Hence, in this study, we evaluated the long-term effects of a 20% high fructose diet (HFD) and global cerebral ischemia on neurological, cognitive and emotional performance in three-month-old male Wistar rats. Results Our results demonstrated that fructose intake led to increases in body weight and blood glucose, as well as reduced insulin sensitivity. The co-morbidity of fructose intake and cerebral ischemia resulted to hyperlipidemia, as well as increases in liver and adipocyte damage, which worsened neurological performance and resulted in alterations in learning and emotional skills at two weeks post-ischemia. No significant biochemical changes in autophagy and plasticity markers at the late stage of ischemia were observed. Conclusion These results suggested that obesity causes a lasting effect on metabolic disorders that can contribute to increased neurological impairment after cerebral ischemia.Sexual and gender minority youth (SGMY) have higher rates of bullying than their heterosexual peers and must disproportionately cope with bullying victimization. The purpose of this research is to highlight various coping strategies employed by SGMY. We conducted 20 cross-sectional, semi-structured online interviews with SGMY about their bullying experiences and coping strategies. We coded interviews with descriptive qualitative research to illustrate a comprehensive summary of bullying-related coping methods. We found SGMY engage in multiple coping strategies that include (1) emotion-focused coping-rumination; self-harm and considering or attempting suicide; seeking social and emotional support; engaging in creative endeavors; self-acceptance and community connectedness-and (2) problem-focused coping-reporting the bully; confronting the bully; conceal orientation; ignoring the bullying; and changing environment. Additionally, most SGMY reported using multiple coping techniques or changing how they coped over time (i.e., coping flexibility). These findings can inform future interventions to promote positive coping mechanisms among SGMY.Objectives. This article describes the effects of two specific information and communication technology (ICT) demands (telepressure, technostress creators) on employee well-being, and investigates a mediating effect of detachment (Study 1) and moderating effects of technostress inhibitors on the effects of ICT demands on well-being (Study 2) and detachment (Study 3). Methods. Three quantitative studies with employees (Study 1, N = 296; Study 2, N = 142; Study 3, N = 316) were conducted. Results. The results support the negative effect of ICT demands on several well-being indicators. They also show how detachment mediates the effect of telepressure on well-being (Study 1) and how technostress inhibitors moderate the effect of technostress creators on well-being (Study 2). Technostress inhibitors further buffer negative effects of technostress creators on detachment (Study 3). Conclusion. Interventions to reduce negative consequences of ICTs by increasing the level of technostress inhibitors (e.g., technical support) or facilitating employee detachment (e.