https://www.selleckchem.com/products/n-acetyl-dl-methionine.html Conclusion This study will present comprehensive evidence to determine whether mRNA 25 expression in serum is associated with LC, and will provide helpful evidence for the future studies. Systematic review registration INPLASY202040056.Background The goal of this study is to assess the therapeutic effect of Xuebijing combined with thymosin (XBJ-T) for the treatment of patients with hemorrhagic fever with renal syndrome (HFRS). Methods We will search the electronic databases of Cochrane Library, PUBMED, EMBASE, PsycINFO, Scopus, Opengrey, Cumulative Index to Nursing and Allied Health Literature, Web of Science, Google scholar, Allied and Complementary Medicine Database, and Chinese Biomedical Literature Database from inception to the present. No language and publication status will be employed in this study. Based on the predefined eligibility criteria, selection of study and data extraction will be performed by 2 researchers independently. Study quality will be assessed using Cochrane risk of bias tool. We will apply RevMan 5.3 software to pool and analyze the extracted data. Results This study will assess the therapeutic effect of XBJ-T for the treatment of patients with HFRS. Conclusion The findings of this study may provide systematic evidence to judge whether XBJ-T is an effective and safety intervention for HFRS. Study registration number INPLASY202040068.Background Femoral head avascular necrosis (FHAN) is a very common condition among elderly population. Previous studies have reported that total hip arthroplasty (THAP) can benefit patients with such condition. However, no study systematically addressed this topic. Thus, this study will systematically explore the efficacy and safety of THAP for the treatment of patients with FHAN. Methods We will search the following electronic bibliographic databases from inception to the February 29, 2020 MEDLINE, EMBASE, Cochrane Library, Cumulative Index to N