Surgically assisted rapid maxillary expansion (SARME) is a common technique developed to treat skeletally mature patients with transverse maxillary deficiency. Although SARME is supposed to be a relatively safe procedure, it is not completely free of complications. The purpose of this study was to reveal the most typical postoperative SARME complications. Retrospective evaluation of the clinical cases of 665 patients (247 males and 418 females, mean age 25,3 years) with the diagnosis of maxillary transverse deficiency, who underwent SARME in period between 2012 and 2017 at the Clinical Center of Maxillofacial, Plastic Surgery and Dentistry, Moscow. According to the results of the research, the most typical complications of SARME are paresthesia of the infraorbital nerve branches and nasopalatine nerve (198/665), distraction device dislocation (61/665), inflammation in the distraction device area (57/665), insufficient expansion of the maxilla (42/665), asymmetric expansion (27/665). The number of complications revealed indicates that SARME is an operation associated with the risks of postoperative complications. Careful treatment planning, following the operation protocol and performing the minimally invasive access can help to avoid the majority of complications.Chronic generalized parodontitis is one of the most prevalent disorders among diseases of oral cavity, making the search for optimal treatment modalities of this disorder one of the mostressing matters to this day.  The purpose of this study was to assess outcomes of conventional therapy and secondary prevention of chronic generalized parodontitis with in combination with use of laser therapy and antioxidant drug treatment.  The study is presented as a joint multi-site investigation conducted by the group of authors from St. Petersburg and Saransk medical teaching and clinical institutions. The aim of the study was to improve the treatment and secondary prevention of chronic generalized parodontitis based on a pathogenetically substantiated scheme of laser and antioxidant therapy.  The total of 98 patients (31 male and 67 female) aged 30-50 years) with the 3 to 10 year history of moderate chronic generalized parodontitis were selected for the prospective study.  All patients were approximately equally divided into three groups according to the received treatment regimens conventional treatment, laser therapy, and laser therapy with antioxidant medication. Several clinical indices were utilized for parodontal tissue assessment (PMA, SBI, AP), resistance of gingival capillary bed, osteal resorption. The lipid peroxide oxidation was determined by MDA, Fe2+ MDA  and phospholipase A2.  Additional implementation of laser and metabolic therapies sufficiently increases efficacy of conventional therapy and improves secondary prevention of chronic parodontitis. A marked decrease in structural-functional deviations and apparent recovery of microcirculatory vascular bed of parodontal tissue has been achieved. .Periodontitis is the most common oral disease worldwide and is the leading cause of tooth loss. It is considered to be a major burden in terms of costs of treatment and preventive measures. According to the systematic reviews, there is a link between periodontitis and cancer. In particular, patients diagnosed with periodontitis have a higher risk of developing oral cancer. In this regard, the histomorphological examination of patients with periodontitis, which has not yet been sufficiently introduced in dental practice, is acquiring more and more importance. The aim of the work is a morphological study of periodontal tissues in patients with severe generalized periodontitis in Georgia - to identify signs of possible precancerous lesions.  https://www.selleckchem.com/products/liraglutide.html  The data obtained show that the morphological characteristic of severe periodontitis is purulent destructive inflammation. In addition, a third of severe periodontitis is accompanied by mild to moderate epithelial dysplasia, which should be taken into account when choosing a treatment method in terms of oncological alertness.Along with sexually transmitted infections opportunistic pathogens and normal microbiota are becoming increasingly clinically important. Opportunistic pathogens can lead to purulent-inflammatory process of the genitals The aim of the current work was to detect qualitative and quantitative composition of vagina contents in non-specific bacterial vaginosis. Vaginal microbiota of 298 women aged from 16 to 64 years old was analyzed. Examination was provided by polymerase chain reaction. In normocenosis with domination of enterobacteria the prevalence index of conditionally-pathogenic microflora wasn't more than 3 lg GE/sample. With absence of mycoplasmas the quantity of conditionally-pathogenic microorganisms wasn't more than 104,5. At same time in patients with dysbiosis of I and II levels index of conditionally-pathogenic microflora was from 3 to 1 and less than 1 lg GE/sample accordingly; there was diagnosed a significant decrease of the total bacterial mass. Simultaneously, decreasing of Lactobacillus quantity (more expressed in dysbiosis-II) meanwhile appearance of mycoplasmas and utmost constant quantity of Candida was revealed. A comprehensive determination of a wide range of opportunistic pathogens on the background of normal flora in the vaginal discharge of women of different ages had been studied.The aim - to assess the body size of patients with polycystic ovary syndrome to study their somatotypes and component composition of body weight. To solve the goals and objectives, were prospectively examined 105 women aged 20 to 36 years of different morphotypes. These patients were interviewed according to a specially designed questionnaire and divided into groups 50 women with multifollicular ovarian structure and 25 - women with polycystic ovary structure. The comparison group consisted of 30 women without disturbances of ovarian structure (healthy women). The body surface area of women with PCOS was significantly larger than in patients of the comparison group and the control group. It was also noted that patients with multifollicular structure of the ovaries had a significant increase in body area from healthy women (p less then 0,05). The mass-growth rate was significantly higher in patients with polycystic ovary structure compared to patients diagnosed with multifollicular ovarian structure and patients in the control group (p less then 0.