https://www.selleckchem.com/products/ff-10101.html While scientific uncertainty always invites the risk of politicization and raises questions of how to communicate about science, this risk is magnified for COVID-19. The limited data and accelerated research timelines mean that some prominent models or findings inevitably will be overturned or retracted. In this research, we examine the attitudes of more than 6000 Americans across five different survey experiments to understand how the cue giver and cue given about scientific uncertainty regarding COVID-19 affect public trust in science and support for science-based policy. Criticism from Democratic political elites undermines trust more than criticism from Republicans. Emphasizing uncertainty in projections can erode public trust in some contexts. Downplaying uncertainty can raise support in the short term, but reversals in projections may temper these effects or even reduce scientific trust. Careful science communication is critical to maintaining public support for science-based policies as the scientific consensus shifts over time.Enzymatic processing of fish by-products for recovery of peptides (hydrolysates) is a promising technology to reach food grade ingredients of high nutritional quality. Despite this, their bitter taste and "fish" odor block implementation in food products and limit their economic potential. Trimethylamine (TMA) is a known contributor to malodor in fish. Current strategies to mask or remove the odor either are not effective or give rise to undesirable side effects. As an alternative approach to remediate TMA, we propose a novel enzymatic strategy to convert TMA into the odorless trimethylamine N-oxide (TMAO) using TMA monooxygenases (Tmms). We identified a diverse set of bacterial Tmms using a sequence similarity network. Purified, recombinant enzymes were assessed for their biocatalytic capacity by monitoring NADPH consumption and TMAO generation. Selected Tmms were subjected to biochem