ection and the mechanisms used by these viruses to avoid clearance through the autophagic pathway. Our study highlights the importance of the host factor BPIFB3 in regulating flavivirus replication and further confirms that the RETREG1-dependent reticulophagy pathway is antiviral to both DENV and ZIKV. Copyright © 2020 American Society for Microbiology.Globally, drug regulators have approved statins for the prevention of cardiovascular disease (CVD), although their use in primary prevention has been controversial. A highly publicised debate has ensued over whether the benefits outweigh the harms. Drug regulators, which are legally required to make independent judgements on drug approvals, have remained silent during the debate. Our aim was to navigate the decision-making processes of European drug regulators and ultimately request the data upon which statins were approved. Our findings revealed a system of fragmented regulation in which many countries licensed statins but did not analyse the data themselves. There is no easily accessible archive containing information about the licensing approval of statins or a central location for holding the trial data. This is an unsustainable model and serves neither the general public, nor researchers. © Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions.  https://www.selleckchem.com/products/vit-2763.html  Published by BMJ.Breast density has been a critical topic in mammography and women's health for several years. Many states have created laws and mandates to ensure that patients and ordering providers receive information regarding a patient's breast density. Mammographers and patients must understand breast density classifications and how they can affect clinical assessment, diagnosis, and treatment. During an examination, understanding breast density can improve a mammographer's ability to achieve images of diagnostic quality, while ensuring the patient remains as comfortable as possible. © 2020 American Society of Radiologic Technologists.Idiopathic pulmonary fibrosis (IPF) is an uncommon and fatal lung disease that causes the lung tissue to become progressively stiff and scarred. It is a type of interstitial lung disease that radiographers might encounter on the job. Chest radiography and high-resolution computed tomography of the lungs are necessary for diagnosing and treating IPF. This article describes the suspected causes and usual progression of IPF, diagnostic techniques, treatments, and prognosis. © 2020 American Society of Radiologic Technologists.Although magnetic resonance (MR) imaging does not use ionizing radiation, it has its own safety issues. MR safety concerns are associated with the static magnetic field, radiofrequency burns, scanner acoustic noise, and the use of gadolinium-based contrast agents. MR technologists have a responsibility to thoroughly screen patients and personnel before they enter the magnetic field and to research patient implants and devices to determine under what conditions the patient can be scanned safely. During long scans, MR technologists also must monitor patients to avoid adverse events. This article is useful for non-MR technologists who might work in the MR environment or who are considering cross-training in this important discipline. © 2020 American Society of Radiologic Technologists.PURPOSE To explore medical imaging and radiation therapy professionals' perceptions of publishing in academic journals. METHODS Using a descriptive survey approach, a random sample of American Society of Radiologic Technologists (ASRT) members was invited to share their experiences with publishing, including motivating factors, perceived challenges, and support measures to benefit new writers. Percentages and descriptive statistics were used to analyze the data. RESULTS There were 261 completed responses analyzed for this study. The majority (141, 54%) of the participants thought it was very important to publish in academic journals; however, only 26 (10%) of the participants indicated that they had published an article in an academic journal. Of the remaining 235 participants, 42 (17.9%) stated that they were interested in publishing an article in an academic journal. DISCUSSION Participants who had publishing experience were motivated by personal satisfaction and gratification, and participants who expressed an interest in publishing indicated they would be motivated to do so by having an improved understanding of the publication process. Both groups indicated that lacking the time to write was the greatest perceived barrier to publishing. In addition, participants who had published thought writing with an experienced author would be most beneficial to new authors, while participants who were interested in publishing thought attending a technical writing workshop would be most beneficial to new writers. CONCLUSION To increase the number of published articles in the medical imaging and radiation therapy profession, organizations like the ASRT should consider establishing or increasing programs that support medical imaging and radiation therapy professionals in their writing and publishing endeavors. © 2020 American Society of Radiologic Technologists.PURPOSE To assess the status of quality management systems in computed tomography (CT) facilities in Ghana. METHODS A questionnaire and quality control measurements were used to assess the status of quality management systems in CT facilities in Ghana. Thirty-one CT facilities took part in the study. The evaluation included quality assurance (QA), quality control (QC), and quality improvement (QI). RESULTS Seventeen (54.8%) of the 31 CT facilities had a QA-QC committee in place to ensure patient protection. Fifteen facilities (48.4%) had documented protocols for CT scanning. Ten facilities (32.3%) lacked QC assessment and recordkeeping after notable repairs. Regular QC check records were available in 20 (64.5%) facilities. All scanners passed the QC assessments; however, none of the facilities had established local diagnostic reference levels. DISCUSSION Quality management systems in some Ghanian CT facilities are unsatisfactory; not all facilities have the needed infrastructure in place for quality management system purposes.