While this may (or may not) sit well with Mr Lehrer, who at the time of this writing is still living, I hope it does not cause further discomfiture to the collective eternal peace of Professor Dimitri Mendeleev, Sir William Schwenk Gilbert and Sir Arthur Sullivan. Nonetheless, I will use this preface to take departure for the primary subject of this manuscript, namely our efforts on selenium, which is where it all got started.Mechanical tradeoffs in performance are predicted to sculpt macroevolutionary patterns of morphological diversity across environmental gradients. Water depth shapes the amount of wave energy organisms experience, which should result in evolutionary tradeoffs between speed and maneuverability in fish swimming morphology. Here, we tested whether morphological evolution would reflect functional tradeoffs in swimming performance in 131 species of wrasses and parrotfish (Family Labridae) across a water depth gradient. We found that maximum water depth predicts variation in pectoral fin aspect ratio (AR) in wrasses, but not in parrotfish. Shallow-water wrasses exhibit wing-like pectoral fins that help with 'flapping', which allows more efficient swimming at faster speeds. Deeper water species, in contrast, exhibit more paddle-like pectoral fins associated with enhanced maneuverability at slower speeds. Functional morphology responds to a number of different, potentially contrasting selective pressures. Furthermore, many-to-one mapping may release some traits from selection on performance at the expense of others. As such, deciphering the signatures of mechanical tradeoffs on phenotypic evolution will require integrating multiple aspects of ecological and morphological variation. As the field of evolutionary biomechanics moves into the era of big data, we will be uniquely poised to disentangle the intrinsic and extrinsic predictors of functional diversity.Background Concerns are being raised about the impact of inadequate safety equipment on the mental health of healthcare workers during the COVID-19 medical response. Aims To assess the impact of inadequate safety equipment on the mental health of service personnel deployed on operations in order to better understand the impact on those working under the similarly demanding conditions of the COVID-19 medical response. Methods Self-report surveys were conducted in four operational environments with 3435 personnel providing data. Surveys recorded data on socio-demographic, military and operational characteristics, mental health measures and specific occupational stressors. Analysis through logistic regression explored the association between inadequate equipment and all other factors. Results A total of 3401 personnel provided data on their perceptions of the adequacy of their equipment, of which 532 (15%) stated that they had a lot of concerns that they did not have the right equipment in working order. Analysis found significantly greater odds of reporting symptoms of common mental health disorders (CMD), 2.49 (2.03-3.06), post-traumatic stress disorder (PTSD), 2.99 (2.11-4.24), poorer global health 2.09 (1.62-2.70) and emotional problems 1.69 (1.38-2.06) when individuals reported working with inadequate equipment. Analyses remained significant when adjusted for confounding factors such as rank, sex and operational environment. Conclusions An individual's perception of having inadequate equipment is significantly associated with symptoms of CMD, probable PTSD, poorer global health and increased reporting of emotional problems. This in turn may impact on their ability to safely carry out their duties and may have longer-term mental health consequences.Ghost moths in the genus Thitarodes Viette, 1968, are hosts of the economically important caterpillar fungus, which is harvested in high mountain meadows across the Hengduan mountains and the Himalayas. In northwestern India, although caterpillar fungus has been collected in the state of Uttarakhand, no adults of Thitarodes species have been recorded. We report the sighting of a female pupa of Thitarodes sp. and its last-instar molt at Munsiyari, Uttarakhand, India, on 5 July 2019 and estimate that the adult emergence time in this habitat should be late July or early August. Although the habitats of caterpillar fungus in Uttarakhand are geographically closer to those in Nepal, they are climatically more similar to habitats of caterpillar fungus in Qinghai province in China. Among records at the same elevation, climatic variables are highly predictive of the emergence date of Thitarodes adults (adjusted-R2 0.7925, F = 6.27, P = 0.03). Our result highlights the role of the Himalayan mountains as both a north-south climatic barrier and an east-west climatic gradient. We encourage local stakeholders and scientists in Uttarakhand to survey adult emergences of Thitarodes from July to mid-August.Background Chronic pain (CP) remains the second commonest reason for being off work. Tertiary return to work (RTW) interventions aim to improve psychological and physical capacity amongst workers already off sick. Their effectiveness for workers with CP is unclear. Aims To explore which tertiary interventions effectively promote RTW for CP sufferers. Methods We searched eight databases for randomized controlled trials evaluating the effectiveness of tertiary RTW interventions for CP sufferers. We employed the Cochrane Risk of Bias (ROB) and methodological quality assessment tools for all included papers. We synthesized findings narratively. Meta-analysis was not possible due to heterogeneity of study characteristics. Results We included 16 papers pertaining to 13 trials. The types, delivery format and follow-up schedules of RTW interventions varied greatly. Most treatments were multidisciplinary, comprising psychological, physical and workplace elements. Five trials reported that tertiary interventions with multidisciplinary elements promoted RTW for workers with CP compared to controls. We gave a high ROB rating for one or more assessment criteria to three out of the five successful intervention trials. Two had medium- and low-risk elements across all categories. One compared different intensity multidisciplinary treatment and one comprised work-hardening with a job coach. Seven trials found treatment effects for secondary outcomes but no RTW improvement. Conclusions There is no conclusive evidence to support any specific tertiary RTW intervention for workers with CP, but multidisciplinary efforts should be considered.  https://www.selleckchem.com/products/Thiazovivin.html  Workers' compensation is an important area for RTW policymakers to consider.