Immune profile assessment-particularly for SLE-and subsequent specific therapy are beneficial in patients with persisting unexplained hyperkalemic or hypokalemic paralysis, especially in case of isolated RTA. © 2020 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.Diffuse large B-cell lymphoma often presents with extranodal manifestations involving the musculoskeletal system. Shoulder pain is particularly worrisome for malignancy. Individuals presenting with refractory upper extremity complaints should undergo a prompt and thorough evaluation for cancer, as a delay in diagnosis can result in an unfavorable outcome. © 2019 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.Clear cell sarcoma of the esophagus is very rare. The etiology of this neoplasm remains unknown. Confirmed diagnosis requires histopathology with immunochemistry and molecular study. CCS typically shows highly aggressive behavior with a high rate of local recurrence, metastases, and death from disease. © 2019 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.Ventricular noncompaction or hypertrabeculation is rare and unclassified cardiomyopathy that mostly affects the left ventricle. We report the case of biventricular hypertrabeculation in a 54-year-old woman who presented with congestive heart failure de novo associated with arrhythmia in a low-income setting. We also discussed the therapeutic challenges.  https://www.selleckchem.com/products/resatorvid.html  © 2020 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.This case suggests a mechanistic rationale for the clinical efficacy of intravenous immunoglobulins (IVIG) in treating CD40 ligand (CD40L) deficiency associated neutropenia as it is the first reported instance of free and cell-bound antineutrophil antibodies in a case of CD40L deficiency, accompanied by a prolonged and clinically severe neutropenia. © 2019 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.Precision medication entails selecting the precise medication, dose, and timing of administration. Multi-drug interactions and genetics significantly affect precision medication. In this article, we present two simulated cases for real-world applications of precision medication. Clinicians may need to acquire additional skills to apply the principles illustrated by these cases. © 2019 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.This report explains how health system failure can hinder provision of healthcare for a common health problem. Inadequate healthcare delivery can create barriers, lead to stress, prolong waiting time, and affect overall well-being of patients. © 2019 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.Primary appendiceal lymphomas (PAL) are a type of primary gastrointestinal non-Hodgkin lymphoma (PGINHL) with an incidence of less then 1%. There is considerable discordance with regard to the optimal management of PGINHL. We describe two cases of PAL, perform a literature review, and discuss the available evidence for optimal treatment. © 2020 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.Pure red cell aplasia (PRCA) is a rare paraneoplastic syndrome occasionally associated with thymomas. Here, we report on the first ever use of a bovine hemoglobin-based oxygen carrier, HBOC-201 (HbO2 Therapeutics LLC; Hemopure®, Waltham, MA) for the supportive management of pure red cell aplasia in a Jehovah Witness patient. © 2019 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.Performing a supplementation intervention with creatine and protein, in conjunction with low-intensity endurance and resistance exercise is safe and has a positive effect on the quality of life in a patient with desminopathy. © 2019 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.This clinical report describes the expeditious treatment of a geriatric patient with squamous cell carcinoma of the nose treated with total rhinectomy, craniofacial implant placement, and a nasal prosthesis. © 2019 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.Primary biliary cholangitis is associated with hyperlipidemia, but studies show that the condition does not increase cardiovascular risks. The case presents acute ischemic stroke with no underlying risk factors and subsequent new diagnosis of primary biliary cholangitis, which can suggest possible association between primary biliary cholangitis and acute stroke. © 2019 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.Venetoclax with high-dose methotrexate and rituximab seem effective and safe to treat central nervous system involvement of chronic lymphocytic leukemia. © 2019 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.Mycosis fungoides (MF) is the most common type of cutaneous T-cell lymphoma (CTCL). It may arise rapidly in a scar or keloid, presumably due to a long-standing proliferative state or autoimmune theory. There should be a low threshold for performing a skin biopsy if unusual lesions develop at those sites. © 2020 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.This case report is meant to widen the scope of lesion locations in posterior reversible encephalopathy syndrome (PRES) to include the brainstem, frontal lobe, and basal ganglia in order to increase the diagnosis and treatment of PRES. © 2019 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.Takayasu's arteritis should be kept under the differential diagnosis of stroke in all young patients. Early, proper diagnosis and treatment are necessary to reduce any further progression, morbidity, and mortality rates of the disease. © 2019 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.This paper reports the case of a 46-year-old woman suffering from bipolar disorder of type I with mixed features with initial fronto-temporal atrophy. Although considered treatment-resistant to conventional strategies, she successfully responded to a combination of rivastigmine, clozapine, and oxcarbazepine. © 2020 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.