https://www.selleckchem.com/products/bay-1000394.html This paper proposes a solution for events classification from a sole noisy mixture that consist of two major steps a sound-event separation and a sound-event classification. The traditional complex nonnegative matrix factorization (CMF) is extended by cooperation with the optimal adaptive L1 sparsity to decompose a noisy single-channel mixture. The proposed adaptive L1 sparsity CMF algorithm encodes the spectra pattern and estimates the phase of the original signals in time-frequency representation. Their features enhance the temporal decomposition process efficiently. The support vector machine (SVM) based one versus one (OvsO) strategy was applied with a mean supervector to categorize the demixed sound into the matching sound-event class. The first step of the multi-class MSVM method is to segment the separated signal into blocks by sliding demixed signals, then encoding the three features of each block. Mel frequency cepstral coefficients, short-time energy, and short-time zero-crossing rate are learned with multi sound-event classes by the SVM based OvsO method. The mean supervector is encoded from the obtained features. The proposed method has been evaluated with both separation and classification scenarios using real-world single recorded signals and compared with the state-of-the-art separation method. Experimental results confirmed that the proposed method outperformed the state-of-the-art methods.Over the past decade, short non-coding microRNAs (miRNAs), including circulating and fecal miRNAs have emerged as important modulators of various cellular processes by regulating the expression of target genes. Recent studies revealed the role of miRNAs as powerful biomarkers in disease diagnosis and for the development of innovative therapeutic applications in several human conditions, including intestinal diseases. In this review, we explored the literature and summarized the role of identified dysregulated fe