https://www.selleckchem.com/products/odm-201.html To evaluate the difference in quality of fracture reduction between the sinus tarsi approach (STA) and extensile lateral approach (ELA) using postoperative CT scans in displaced intra-articular calcaneal fractures (DIACFs). Retrospective SETTING Level 1 and Level 2 academic centers. Consecutive patients undergoing operative fixation of DIACFs with post-operative CT scans and standard radiographs. Patients were identified based on CPT code and chart review. All operative calcaneal fractures treated between 2012-2018 by fellowship trained orthopaedic trauma surgeons were evaluated. Those with both post-operative CT scans and radiographs were included. Exclusion criteria included extra-articular fractures, malunions, percutaneous fixation, ORIF and primary fusion, and those patients without a postoperative CT scan. The Sanders classification was used. Cases were divided into 2 groups based on ELA vs. STA. Bohler's angle and Gissane's angle were evaluated on plain radiographs. CT reduction quality gradingr reduction quality (p = 0.06). The extensile lateral approach (ELA) had a better overall reduction of Bohler's angle on plain radiographs and of the posterior facet and tuberosity on postop CT scans. For Sanders type II DIACFs there was no difference between STA and ELA. Importantly for Sanders III DIACFs, ELA trended towards better reduction quality. In addition to fracture reduction, surgeon learning curve, early wound complications and long-term outcomes must be considered in future studies comparing the ELA and STA. Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence. Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence. Androgen deprivation therapy (ADT) is the standard of care for men with nonmetastatic hormone-sensitive prostate cancer (nmHSPC) after treatment failure. Although intermittent ADT (iADT) is noninferior to