https://www.selleckchem.com/products/tmp195.html 3% of patients died, of which 25% died of sepsis and 8.3% died of massive hemorrhage. The registry of IEI provides information about epidemiological data, incidences, prevalence, diagnoses, and treatments, which will favor the development of new health policies for obtaining resources and tools to improve the care models.Food allergy is an immune reaction that occurs frequently at a pediatric age; its prevalence is higher in industrialized countries, affecting 8% of the population in average. The most frequently involved foods are milk, chicken eggs, soy, peanuts, fish, wheat, seafood, and dried fruits. Food allergies can be divided into three groups IgE-mediated, non-IgE-mediated, and mixed food allergy. The symptoms will depend on the immunological mechanisms and they can be divided into immediate or delayed symptoms; immediate symptoms appear during the first two hours after the intake, and delayed symptoms appear after the second hour and up to 72 hours. The diagnosis of food allergies requires the medical history of the patient, a physical examination, and laboratory tests; a misdiagnosis can lead to unnecessary elimination diets. The gold standard is the double-blind, placebo-controlled oral food challenge. The main treatment is food restriction, in which the entailed nutritional and psychological implications must be taken into account. Another treatment option is oral immunotherapy, which is recommended for patients who cannot carry out an elimination diet due to its significant impact on the quality of life. Trimethoprim with sulfamethoxazole (TMP-SMX) is the drug of choice for the prophylaxis of AIDS-associated comorbidities. To compare the efficacy and safety of two schemes of desensitization to TMP-SMX in HIV-positive patients. A study was conducted from March 2018 to October 2019; it included HIV-positive patients who presented an adverse skin reaction to TMP-SMX; fifteen of them received desensitization