29-0.34, 95%CI 0.11, 0.75). Contrarily, density of road junctions was associated with 2.5-6.3 times more hospital admissions for cardiovascular disease hospital admissions (IRR range 2.53-6.34, 95%CI 1.07,17.91). There were no significant association between hospital admission and density of residential area, undeveloped land, rail and bus stations. The shapes of relationships for all attributes were non-linear, and changed markedly at the third quartile except for recreational area density. The findings suggest that land use attributes have some protective effects on the cardiovascular disease admission cases as compared to the transport attributes. These findings have important merits for integrating health into urban planning.
  In vivo dopamine transporter imaging is a useful tool for distinguishing nigrostriatal pathologies (e.g. Parkinson's disease) from other causes of tremor. However, while many of the motoric features of Parkinson's disease (e.g. bradykinesia, rigidity, hypomimia) correlate well with reduced striatal dopamine transporter binding, the same relationship has not been demonstrated for tremor. We investigated the relationship between striatal dopamine transporter binding and quantitative measures of tremor.
 
  23 participants with Parkinson's disease underwent standardised clinical assessment including structured, videotaped clinical examination, tremor neurophysiology study of both upper limbs using accelerometry and surface EMG, and Technitium-99m TRODAT-1 brain SPECT imaging. Normalised striatal uptake values were calculated. Tremor EMG and accelerometry time series were processed with Fourier transformation to identify peak tremor power within a window of 3-10Hz and to calculate the tremor stability index (TSI).
 
  Spearman correlation analyses revealed an association between tremor power and contralaterally reduced striatal uptake in a number of recording conditions. This association was strongest for rest tremor, followed by postural tremor, with the weakest association observed for kinetic tremor. Lower TSI was also associated with lower contralateral striatal uptake in a number of rest and postural conditions.
 
  These data suggest a relationship between Parkinsonian rest tremor and contralateral reduction in striatal dopamine binding. Use of quantitative neurophysiology techniques may allow the demonstration of clinico-pathophysiological relationships in tremor that have remained occult to previous studies.
 These data suggest a relationship between Parkinsonian rest tremor and contralateral reduction in striatal dopamine binding. Use of quantitative neurophysiology techniques may allow the demonstration of clinico-pathophysiological relationships in tremor that have remained occult to previous studies.Despite accumulating evidence suggesting the effectiveness of Attention Bias Modification (ABM) in adults, little is known about its efficacy in children and adolescents. As anxiety has been the chief target in most studies and research in this area has grown rapidly in recent years, we conducted the first meta-analysis to establish the effects of ABM alone for anxiety disorders in children and adolescents. Studies were identified through a systematic search in three main databases PubMed, EMBASE and PsycInfo, resulting in 17 randomized studies. The quality of these studies, possible publication bias and moderators were then examined. ABM had small but significant effects on clinician-rated anxiety symptoms and attention bias towards threat, while the effect on self or parent-reported anxiety measures was non-significant. Evidence quality ranged from moderate to very low. ABM was more effective when conducted as a stand-alone treatment than as an adjunct to other treatments. In addition, younger age and larger number of training sessions were associated with a greater reduction in clinician-rated anxiety symptoms. Results indicate that ABM may have significant effects on anxiety and attention bias in children and adolescents. Overall, the effects of ABM are mainly evident when clinical outcome is assessed by a clinician.To illustrate the main characteristics of the request for and choice of support by a population accessing a dedicated service for people bereaved through suicide.The participants were divided first according to their reason for requesting support and based on their choice of intervention, which were "caring" services (improve knowledge about suicide prevention, postvention and grief support) and "curing" services (psychotherapy, chat groups, and meditation retreats).The study was based on 539 participants, chiefly middle-aged women. Most had lost kin and the time since suicide ranged from 1day to 45 years. The main reasons for contacting the service were seeking help for symptoms (42%), connecting with other suicide survivors (19%); 15% reported not knowing what to ask for. Among the participants, 30% participated in the "curing" interventions; they were slightly older and had more grief symptoms, some above the threshold for complicated grief.  https://www.selleckchem.com/products/ox04528.html  These participants had more often survived a child or partner and more frequently sought contact with other survivors or were more likely to be seeking help for symptoms.The presence on the web of a project specialized in the care of suicide survivors can provide a resource bringing them closer to curing their emotional pain.Research on the effect of a prolonged lockdown on inpatient admissions is limited. In this background, this study was planned, and it included patients admitted to inpatient units of a large mental health network in Melbourne during the lockdown (March 16-September 16, 2020) and a similar time period in 2019. The results showed a 12% decrease in admissions. The lockdown period included patients with lower mean age and more patients with never married status, higher education status, students and patients with home duties, and certain psychiatric diagnoses. Overall, the patients needing inpatient treatment during a prolonged lockdown are different.
  To examine whether the 1
  COVID-19 lockdown in Israel affected emergency psychiatric presentations in a general hospital.
 
  We studied files of patients who underwent psychiatric consultation in the emergency-room (ER) at the Tel-Aviv Sourasky Medical Center during a lockdown imposed in 2020. Parallel data were obtained from 2017-2019, as control.
 
  The number of psychiatric consultations dropped during the lockdown period; an increased relative number of compulsory psychiatric hospitalizations was documented and a decreased rate of consented psychiatric hospitalizations.
 
  Less psychiatric patients approached the ER during the lockdown period, pointing to an urgent need to facilitate access to psychiatric care in future times of crisis.
 Less psychiatric patients approached the ER during the lockdown period, pointing to an urgent need to facilitate access to psychiatric care in future times of crisis.