https://www.selleckchem.com/products/Tretinoin(Aberela).html Caproate production by mixed culture fermentation (MCF) is economically attractive. Xylose is known as the second most abundant sugar in nature, however, producing caproate from xylose is never reported. In this study, caproate production from xylose by mesophilic MCF was firstly investigated. The results showed that as pH decreasing to 5.0, the caproate concentration was 2.06 g/L in a batch reactor and was between 0.45 and 1.07 g/L in a continuously stirred reactor. Microbial analysis illustrated that Caproiciproducens and Clostridium_sensu_stricto_12, as two main identified caproate producers, occupied over 50% and around 10% of mixed culture, respectively. Thus, caproate production from xylose was proposed via the fatty acid biosynthesis pathway, not the well-known reverse β-oxidation pathway. These unexpected differences from literatures gains more understanding about caproate production from organic substrates via MCF. Powdered activated carbon (PAC), lignite activated coke (LAC) and Fe-C carriers were applied to enhance CBFBRs to degrade targeted phenolics. In start-up stage, PAC and LAC equipped CBFBRs with higher environment adaptability and phenolic degradation capacity for phenol (>96%), p-cresol (>91%) and 3, 5-dimethylphenol (>84%) in comparison to Fe-C carrier. In recovery stage, the superior performance was also identified for CBFBRs in basis of PAC and LAC than Fe-C-based reactor. However, the Fe-C carrier assisted CBFBR with more stable degradation performance under impact loading. By comparing microbiomes, significantly enriched Brachymonas (54.80%-68.81%) in CBFBRs exerted primary role for phenolic degradation, and positively contributed to microbial network. Meanwhile, Geobacter in Fe-C-based reactor induced excellent impact resistance by enhancing interspecific electron transfer among microbes. Furthermore, the investigation on functional genes related to phenolic degradation revealed t