https://www.selleckchem.com/Bcl-2.html PURPOSE To compare the Clareon intraocular lens (IOL) with the Tecnis PCB00 IOL in terms of visual performance, refractive outcomes, glistenings occurrence, and quality-of-life outcomes. SETTING Guy's and St Thomas' NHS Foundation Trust, London, England. DESIGN Single-center, single-masked, prospective, randomized, controlled trial. METHODS One hundred thirty-nine patients with bilateral cataracts were randomized to receive the Clareon (C IOL) or Tecnis (T IOL) IOL. Visual acuity, refraction, central corneal thickness (CCT), endothelial cell loss, contrast sensitivity, and mesopic gap acuity, evaluation of glistenings and rates of perioperative and postoperative complications were recorded. Quality-of-life outcomes were measured with the EuroQOL-5 Dimension questionnaire and the Patient-Reported Outcome Measures questionnaire. Optimised A-constants were available for the T IOL but not the C IOL. RESULTS Seventy-one patients (140 eyes) received the C IOL and 68 patients (134 eyes) received the T IOLs. Data wermplications. Surgeon optimization of the A-constant for the Clareon IOL is recommended.PURPOSE To test the performance of 4 tonometers in estimating intraocular pressure (IOP) after 3 forms of refractive surgery. SETTING Eye Hospital, WenZhou Medical University, China. DESIGN Prospective case series. METHODS Patients matched for preoperative age, corneal thickness and myopic correction enrolled for femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK), small-incision lenticule extraction (SMILE), or transepithelial photorefractive keratectomy (TransPRK) were included in the study. For each patient, 4 measurements of IOP were obtained preoperative and 3 months postoperative, using the Goldmann applanation tonometer (GAT-IOP), the Dynamic Contour Tonometer (DCT-IOP), corneal-compensated IOP (IOPcc) from the Ocular Response Analyzer, and biomechanically-corrected IOP (bIOP) from the Corvis ST. Overall corneal stif