This study demonstrated the smallest number of extra stimulations between tachycardia thresholds of 40 and 60 with absolute minimums at 35 and 45. Our results also demonstrate a trend of decreasing extra stimulations per day with increased duty cycle at each tachycardia threshold evaluated.
 
  These data demonstrate the effect of duty cycle and tachycardia threshold on extra stimulations per day and demonstrated the optimal settings for reducing extra stimulations. This research provides reassurance and information to patients and providers about the actual number of stimulations patients receive with AutoStim technology.
 These data demonstrate the effect of duty cycle and tachycardia threshold on extra stimulations per day and demonstrated the optimal settings for reducing extra stimulations. This research provides reassurance and information to patients and providers about the actual number of stimulations patients receive with AutoStim technology.
  The aim of the current study was to compare the risk and also the types of ictal injuries in three groups of people with seizures [i.e., IGE vs. TLE vs. FS].
 
  This was a retrospective study. All patients with an electro-clinical diagnosis of IGE, TLE, or FS were recruited at the outpatient epilepsy clinic at Shiraz University of Medical Sciences, Shiraz, Iran, from 2008 until 2020.  https://www.selleckchem.com/products/beta-aminopropionitrile.html  Age, sex, age at seizure onset, seizure type(s), and occurrence of ictal injury at any time since the onset of the seizures and its characteristics were registered routinely for all patients at the time of the first visit.
 
  One thousand and one hundred seventy-four patients were studied (481 patients with IGE, 402 people with TLE, and 291 persons with FS). While the groups differed in their demographic and clinical characteristics, the rates of ictal injury did not differ significantly between the groups. Tongue injury was more frequently reported by patients with TLE compared with that by people with IGE or FS. Other types/locations of ictal injury were more or less reported by all three groups of the patients.
 
  Ictal injuries may happen with more or less similar rates among people with epilepsy (IGE and TLE) and those with FS. Ictal injury (rate, type, or location) should not be used as a marker for any specific diagnosis among people with seizures.
 Ictal injuries may happen with more or less similar rates among people with epilepsy (IGE and TLE) and those with FS. Ictal injury (rate, type, or location) should not be used as a marker for any specific diagnosis among people with seizures.Ethanol production in Brazil is projected to double between 2012 and 2030 in order to meet increased global demand, resulting in the expansion of sugarcane cultivation. Sugarcane expansion drives both direct and indirect land-use changes, and subsequent changes in hydrology may exacerbate problems of (local) water scarcity. This study assesses the impacts of projected ethanol-driven sugarcane expansion on agricultural and hydrological drought in Brazil. Drought due to sugarcane expansion is modelled using a spatial terrestrial hydrological model (PCR-GLOBWB) with spatiotemporally variable land-use change and climate change scenarios as input. We compare an ethanol scenario with increased ethanol demand to a reference situation in which ethanol demand does not increase. The results show that, on average, 29% of the Centre West Cerrado region is projected to experience agricultural drought between 2012 and 2030, and the drought deficit in this region is projected to be 7% higher in the ethanol scenario compared to the reference. The differences between the ethanol and the reference scenario are small when averaged over macro-regions, but can be considerable at a local scale. Differences in agricultural and hydrological drought between the ethanol and reference scenario are most notable in the Centre West Cerrado and Southeast regions. Locally, considerable changes may also occur in other regions, including the Northeast Coast and Northern Amazon region. Because the South East and Centre West Cerrado regions are responsible for a large proportion of agricultural production, increased agricultural drought may result in significant economic losses, while increased hydrological drought could exacerbate existing problems of water supply to large metropolitan areas in these regions. The identification of areas at risk of increased droughts can be important information for policy makers to take precautionary measures to avoid negative hydrological impacts of increased ethanol demand.Synthetic hormone 17α-ethinylestradiol (EE2) is not completely removed by conventional wastewater treatment plants and therefore is often detected in surface and groundwater, sludge and sediments. Due to its persistence in the environment and its estrogenic potential, a high removal of EE2 from wastewaters before its disposal has become a concern from an environmental point of view, particularly when considering urban reuse applications. This work investigated the application of advanced processes to treat synthetic municipal wastewater containing EE2 after treatment in a membrane bioreactor (MBR). Two advanced processes were assessed the first is advanced oxidation process (AOP), using hydrogen peroxide (H2O2) and ultraviolet (UV) light (route MBR-AOP) and the second, reverse osmosis (RO), in this case using UV/H2O2 to treat the retentate from RO (route MBR-RO). EE2 concentration in final effluent was one order of magnitude lower in route MBR-AOP than in route MBR-RO. Implications for disposal or water reuse were discussed considering the importance of other water quality parameters as well. Economic estimates for CAPEX, OPEX and total cost were made. The introduction of the oxidative step (UV/H2O2) after MBR caused an increase in the total cost of US$ 0.39/m3. In turn, route MBR-RO increased the total process cost by US$ 0.86/m3, showing that reduction of volume to be treated by UV/H2O2 in this route did not offset the cost associated with the acquisition and operation of RO. The total cost was estimated at US$ 2.47/m3 for MBR-AOP and US$ 2.94/m3 for MBR-RO for a design flow of 10 m³/h.