https://www.selleckchem.com/products/a-674563.html Both surgeons met personally in Brussels in 1950.1,4-Oxaborines represent an expansion of the current array of heteroborines. Herein, we report a new ladder-type bis(1,4-oxaborine)pentacene (BO-Pen), the backbone of which can be regarded as an isoelectronic structure of pentacene. The synthesis begins with a two-fold nucleophilic aromatic substitution followed by a ring-closing reaction. The structure was confirmed by X-ray crystallographic analysis. Compound BO-Pen is stable (even after 160 h) under ambient condition and exhibits very different electronic properties as compared to its all-carbon pentacene analogue (Pen-M). Particularly, it shows bright photoluminescence (73 % relative quantum yield) in both solution and in solid state.The dynamics of cortical neuronal activity plays important roles in controlling body movement and is regulated by connection weights between neurons in a cortex-basal ganglia-thalamus (BGCT) loop. Beta-band oscillation of cortical activity is closely associated with the movement disorder of Parkinson's disease, which is caused by an imbalance in the connection weights of direct and indirect pathways in the BGCT loop. In this study, the authors investigate how the dynamics of cortical activity are modulated by connection weights of direct and indirect pathways in the BGCT loop under low dopamine levels through bifurcation analyses and potential landscapes. The results reveal that cortical activity displays rich dynamics under different connection weights, including one, two, or three stable steady states, one or two stable limit cycles, and the coexistence of one stable limit cycle with one stable steady state or two stable ones. For a low dopamine level, cortical activity exhibits oscillation for larger connection weights of direct and indirect pathways. The stability of these stable dynamics is explored by the potential landscapes.Interactions between glycans and glycan-binding prote