https://www.selleckchem.com/products/pf-9366.html 05). The observed increase in HS was associated with an improved insulin resistance sensitivity (absolute handgrip strength -0.40, = 0.007; relative handgrip strength -0.47, = 0.001) after training, which constitutes an essential element for cardiovascular health. The results suggest that high weekly frequency training give greater benefits for weight loss and cardiometabolic risk factors improvement than a training program with a training session of once a week. Furthermore, the improvement of HS can be achieved with a high weekly frequency training. The results suggest that high weekly frequency training give greater benefits for weight loss and cardiometabolic risk factors improvement than a training program with a training session of once a week. Furthermore, the improvement of HS can be achieved with a high weekly frequency training.The aim of this study was to investigate the effect of two types of eccentric (ECC) overload training on strength, speed, power and change of direction in female basketball players. Twenty amateur basketball players (mean ± SD age 23.67 ± 6.05 years; height 1.73 ± 0.05 m; body mass 80.28 ± 17.67 kg) participated in a randomized trial. The players performed either flywheel inertial training (FIT) (n = 11) or tempo ECC training (TET) (n = 9) for 4 weeks, performing two sessions weekly. Performance characteristics, one repetition back squat (1RM), counter-movement jump (CMJ), squat jump (SJ), 10-metre sprint (10 m), change of direction (COD) and sit and reach flexibility (S&R) were tested pre and post intervention. Post-hoc testing revealed significant improvements in the FIT group for 1RM (p ≤ 0.001; ES = 0.59), 10 m (p = 0.003; ES = -0.54) and CMJ (p ≤ 0.001; ES = 1.04), while significant improvements were revealed in the TET group for 1RM (p = 0.007; ES = 0.71) and S&R (p ≤ 0.001; ES = 0.58). In conclusion, both FIT and TET groups demonstrated a positive training stimulus for increas