https://www.selleckchem.com/products/cabotegravir-gsk744-gsk1265744.html Tendinosis is a chronic degenerative condition. Current research suggests both percutaneous needle tenotomy (PNT) and leukocyte-rich platelet-rich plasma (LR-PRP) may be effective treatments for chronic tendinosis, but no studies have assessed the effectiveness of PNT alone versus PNT with intratendinous LR-PRP for multiple tendon types in a single study. To assess the efficacy of PNT versus PNT + LR-PRP to treat chronic tendinosis. Double-blind, randomized, controlled comparative treatment study. Primary academic institution. A convenience sample of 40 participants who had chronic tendinosis (rotator cuff, wrist extensor, wrist flexor, hip abductor, proximal hamstring, patellar, or Achilles) confirmed via ultrasound, failed conservative treatment, and did not have tendon tears, known coagulopathy, or systemic illnesses. Participants were randomly assigned to PNT (n = 19) or PNT + LR-PRP (n = 21). Participants and outcomes assessors were blinded to treatment assignments. PNT was performed with 20-outcomes at 52 or 104 weeks. Although pain scores were lower after PNT compared to PNT + LR-PRP at 6 weeks, there were no between-group differences in outcomes at 52 or 104 weeks.The present research verified the relationship between gratitude and moral disgust and explored its internal mechanism based on the social norm theory for the first time. In this study, 979 participants were recruited and required to complete the Gratitude Questionnaire (GQ), the Moral Disgust Questionnaire (MD), the Perceived Social Support Scale (PSSS), and the Connor-Davidson Resilience Scale (CD-RISC). Data were then analyzed via structural equation model. The results demonstrated that gratitude indirectly affects moral disgust through the chain path of social support → resilience rather than being directly mediated by social support and resilience. From the perspective of social norm theory, the current research reveals t