https://www.selleckchem.com/products/bay-1217389.html Interventional neuro-oncology encompasses an array of image-guided therapies-intra-arterial chemotherapy, regional drug delivery, chemoembolization, tumor ablation-along with techniques to improve therapy delivery such as physical or chemical blood-brain barrier disruption and percutaneous catheter placement. Endovascular and percutaneous image-guided approaches to the treatment of the brain, eye, and other head and neck tumors will be discussed.Vascular anomalies are broadly classified into two major categories vascular tumors and vascular malformations. Most vascular anomalies are caused by sporadic mosaic gene mutations, and recent genetic studies have advanced our understanding of the molecular pathways involved in their pathogenesis. These findings have suggested new therapeutic approaches to vascular anomalies, focusing on their pathogenetic mechanism. This chapter seeks to integrate an improved molecular understanding within the updated classification system of the International Society for Study of Vascular Anomalies. We emphasize the genetic, radiologic, and interventional aspects of diagnosis and management in hopes of allowing improved multidisciplinary collaboration surrounding these complex and interesting anomalies.The arterial supply of the spinal cord is provided by the spinal branch of the cervical, thoracic, and lumbar intersegmental arteries. While supply is initially provided at each embryonic segment, only a few prominent anterior radiculomedullary arteries remain at the adult stage, including the arteries of the cervical and lumbosacral enlargements as well as a constant upper thoracic contributor. The spinal cord is surrounded by the vasocorona, an arterial network that includes several longitudinal anastomotic chains, notably the anterior and posterior spinal arteries, which respectively supply the central and peripheral components of the intrinsic vascularization. The intrinsic venous cir