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https://www.selleckchem.com/products/ml-si3.html Sarcopenia and metabolic syndrome (MetS) are associated with the prognosis from malignant tumors. However, evidence of the relationship between sarcopenia and MetS among gastric cancer (GC) patients following radical gastrectomy is lacking. This study assessed the association between preoperative sarcopenia and MetS among GC patients and analyzed the prognosis of patients with different malnutrition statuses. We prospectively assessed the preoperative statuses of sarcopenia and MetS among patients who underwent radical gastrectomy from July 2014 to December 2017. We combined sarcopenia and MetS to generate four groups MetS-related sarcopenia group (MSS), sarcopenia group (S), MetS group (MS), and normal group (N). A total of 749 patients with resectable GC were included in this study. Preoperative MetS was associated with sarcopenia (p<0.001). Multivariate logistic regression presented that MetS-related sarcopenia (OR=2.445; p=0.010) and sarcopenia alone (OR=2.117; p=0.001) were independent predictoria and MetS require more medical interventions. Data regarding regionally metastatic cutaneous squamous cell carcinoma of the head and neck (cSCCHN) is limited and derived almost exclusively from Australian and United States (US) institutions. We report the first United Kingdom perspective, with the aims of benchmarking survival outcomes and identifying clinically relevant prognosticators. Ninety-one patients with regionally recurrent cSCCHN treated with curative intent over a ten-year period (2009-2018) were studied retrospectively. Time-to-event analyses were used to estimate oncological outcomes, and log-rank statistics and Cox proportional hazards models used to examine potential prognosticators. Receiver operating characteristics were also used to analyse the influence of nodal disease burden. Parotid involvement (with or without neck involvement) was most common (79.2%), and time to recurrence in those with parotid d
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