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https://www.selleckchem.com/products/jw74.html Due to the abusing of antibiotics, multiple drug-resistant pathogenic bacteria have increasingly emerged. It increases the difficulty of treatment as it directly affects public health by diminishing potency of existing antibiotics. Developing alternative therapeutic strategies is the urgent need to reduce the mortality and morbidity related to drug-resistant bacterial infections. In the past 10 to 20 years, nanomedicines have been widely studied and applied as an antibacterial agent. It has become a novel tool for fighting resistant bacteria. The most common innovative substance, metal and metal oxide nanoparticles (NPs), has been widely reported. Until recently, DNA nanostructures used alone or functionalized with specific DNA sequences many scholars for antimicrobial purpose which alternatively selected as therapy for bacterial severe infections. It is a potential candidate of treatments and has a considerable prospect of killing antibiotic-resistant bacteria. This review involves the dimensions of multidrug resistance and the mechanism of bacteria developing drug resistance. The importance of this article is that we summarized the current study of nano-materials based on nucleic acids in antimicrobial use. Meanwhile, the current progress and the present obstacles for its antibacterial therapeutic use and special function of stem cells in this field would also be discussed.With the rapid development of nanotechnology, various nanomaterials have been applied to bone repair and regeneration. Due to the unique chemical, physical and mechanical properties, nanomaterials could promote stem cells osteogenic differentiation, which has great potentials in bone tissue engineering and exploiting nanomaterials-based bone regeneration strategies. In this review, we summary current nanomaterials with osteo-induction ability, which could be potentially applied to bone tissue engineering. Meanwhile, the unique properties of these na

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