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https://www.selleckchem.com/products/l-name-hcl.html Imaging of musculoskeletal disorders, including arthritis, infection, osteoporosis, sarcopenia, and malignancies, is often limited when using conventional modalities such as radiography, computed tomography (CT), and MR imaging. As a result of recent advances in Positron Emission Tomography (PET) instrumentation, total-body PET/CT offers a longer axial field-of-view, higher geometric sensitivity, and higher spatial resolution compared with standard PET systems. This article discusses the potential applications of total-body PET/CT imaging in the assessment of musculoskeletal disorders."The initial experience of using total-body PET/computed tomography (CT) (uExplorer) in Zhongshan Hospital, Fudan University, is described. Compared with conventional PET/CT, total-body PET/CT imaging provides more comprehensive information for evaluation of disease. Using fludeoxyglucose F 18, regular-dose (3.7 MBq/kg), low-dose (1.85 MBq/kg), or extra low-dose (0.37 MBq/kg) scanning, as well as high-quality imaging, protocols were used in clinical practice according to the situation. Dynamic studies were also used to assess tumor biological characteristics or for radiotracer angiography."New protocols for imaging cancer have been developed to take advantage of the improved imaging capabilities of long axial field-of-view PET scanners. Both research and clinical applications have been pursued with encouraging early results. Clinical studies have demonstrated improved image quality and the ability to image with less injected activity or for shorter duration. With the increased sensitivity inherent in total-body PET scanners and new imaging paradigms, new challenges in image interpretation have emerged. New research applications have also emerged, including dosimetry, cell tracking, and dual-tracer applications.The high sensitivity and total-body coverage of total-body PET scanners will be valuable for a number of clinical and researc

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