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https://www.selleckchem.com/products/bay-805.html Because viruses still represent a significant threat to human and animal health worldwide, the development of effective weapons against viral infections remains a top priority for the biopharmaceutical industry. This article reviews the dietary and pharmaceutical applications of polysaccharides (PS), first of all chitosan, in the prevention and treatment of viral diseases, focusing more particularly on solid or gel micro/nanoparticulate systems. The intrinsic antiviral activity of PS and their immunostimulatory effects, implemented in animal and human diets, are first surveyed. Then the review discusses the potential of PS-based particles as carriers of antiviral drugs and vaccines, with emphasis on the adjuvant potency of PS in solid vaccine formulations. The gap between the abundance of academic studies in this area and the lack of actual antiviral formulations dispensed to human patients is underlined, notwithstanding a number of branded products on the market.Mesocriconema abolafiai n. sp. is described by morphological, morphometric, and molecular approaches. The new species is characterized by a body slightly curved with 402 to 612 μm length, 90 to 113 cuticular body annuli with smooth to irregular margins lacking of crenation with not more than one anastomoses, lip region not offset, small flattened submedian lobes, stylet robust (52.8-60.0 µm) with well-developed knobs, open vulva with simple anterior lip, straight vagina, filled spermatheca with globular sperms, presence of males, and conical-acute tail with last annulus bilobed or rounded. Discussions are made on the characterization of M. abolafiai n. sp. from the most closely related species, M. ozarkiense, and several other species having similar tail shape. Furthermore, results of phylogenetic analyses inferred from D2 to D3 expansion fragments of 28S rRNA, 18S rRNA, and ITS rRNA gene sequences revealed the phylogenetic position of the new species within
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