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https://www.selleckchem.com/products/vorapaxar.html Critical illness myopathy (CIM), critical illness polyneuropathy (CIP), and critical illness polyneuromyopathy (CIPNM) are the group of disorders that are commonly presented as neuromuscular weakness in intensive care unit (ICU) settings. They are responsible for prolonged ICU stay and failure to wean off from mechanical ventilation.1 We report one such case of young female who was admitted with undiagnosed type I diabetes mellitus with diabetic ketoacidosis with severe hypokalemia with sepsis developed acute-onset quadriplegia and diaphragmatic palsy within 72 hours of ICU admission. Detailed investigation led to the diagnosis of critical illness polyneuromyopathy. In view of high morbidity, mortality, and poor prognosis, a guided approach to diagnoses and treatment in earliest possible duration might give better improvement and outcome of the illness. Despite all the odds, our patient showed good clinical improvement and finally got discharged. Mahashabde M, Chaudhary GA, Kanchi G, Rohatgi S, Rao P, Patil R, Reply to the Letter to Editor Regarding "An Unusual Case of Critical Illness Polyneuromyopathy". Indian J Crit Care Med 2020;24(7)604-605. Mahashabde M, Chaudhary GA, Kanchi G, Rohatgi S, Rao P, Patil R, et al. Reply to the Letter to Editor Regarding "An Unusual Case of Critical Illness Polyneuromyopathy". Indian J Crit Care Med 2020;24(7)604-605.Critical illness polyneuromyopathy is a growing concern in intensive care units, but its presentation within 24-48 hours of admission is very unusual. Such presentations should be carefully scrutinized, especially in the presence of severe hypokalemia. Sulakshana S, Naik BK. Critical Illness Polyneuromyopathy and the Diagnostic Dilemma. Indian J Crit Care Med 2020;24(7)603. Sulakshana S, Naik BK. Critical Illness Polyneuromyopathy and the Diagnostic Dilemma. Indian J Crit Care Med 2020;24(7)603.How to cite this article Praveen Kumar G, Govil D, Gupta S. Reply to 'Ski

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