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https://www.selleckchem.com/products/vps34-in1.html A factorial design is a cost-effective way to determine the effects of combinations of interventions in clinical research, but it poses challenges that need to be addressed in determining appropriate sample size and statistical analysis.In addition to the prone position or the supine position, some scholars have observed and discussed the therapeutic effect of acupuncture in other body positions, but their criteria are different and individual differences in body position have not been analyzed. According to the relevant discussions in The Inner Canon of Yellow Emperor and with reference to the clinical practice of acupuncture treatment, this article explores the criteria for body position selection, in order to provide guidance for clinical acupuncture treatment.Axon guidance cues includes Slit, Semaphorin, Ephrin and Netrin. They have the function of regulating the regeneration of axons and guiding the regenerated axons to the correct target. They can affect the nervous system, cardiovascular system, and participate in the proliferation and migration of tumor cells. The current research on the influence of acupuncture and moxibustion(mainly focusing on electroacupuncture) on axon guidance cues is limited to animal experiments. Electroacupuncture can treat diseases dominated by the nervous system by regulating the expression of axon guidance cues. This review summarizes the research progress of acupuncture and moxibustion on regulating axonal guidance cues, is hoped to provide references for the mechanism of acupuncture and moxibustion in treating nervous system disease and ideas for acupuncture treatment of diseases related to axon guidance cues.Traditional moxibustion treatment mainly relies on doctors using specific techniques to stimulate the patient's acupoints with ignited moxa sticks. In view of the poor reproducibility, and different methods of different doctors, difficult to carry out quantitative and qua

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