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https://www.selleckchem.com/products/skl2001.html Developing highly efficient Ir-based electrocatalysts for the oxygen evolution reaction (OER) has been an important agenda in spearheading the water splitting technology. In this study, the synthesis of IrCo nanocacti on CoxSy nanocages (ICS NCs) is demonstrated by utilizing CoO@CoxSy nanoparticles as reactive nanotemplates. In addition to the high catalytic activities with a low overpotential of 281 mV at 10 mA cm-2 and an outstanding mass activity of 1285 mA mgIr-1 at 1.53 V, the ICS NCs endure a prolonged OER test for over 100 h, greatly outperforming other previously reported Ir-based electrocatalysts. This work suggests that the unique hetero-nanostructure of IrCo/CoxSy induces in situ S doping during electrochemical oxidation and the beneficial effect of S doping on the enhanced stability of ICS NCs for the OER.Osteoarthritis is a chronic and irreversible degenerative disease that often occurs in middle-aged and elderly people. Although many clinical therapeutics like intra-articular drug injection have been widely used for treating osteoarthritis, there are still some shortcomings that need to be overcome such as frequent injection, inflammatory response, and potential overdose. Inspired by the natural biocompatible lubricant substances, hyaluronic acid (HA), a novel bio-inspired lubricant drug delivery microcarrier with pathological-state responsive switches, was developed for osteoarthritis treatment. In this system, a temperature-responsive hydrogel was used to form an inverse opal-structured microsphere scaffold to increase the drug loading efficiency, while HA was employed as a vehicle to encapsulate drugs. Due to the properties of the scaffold, the loaded lubricant and encapsulated drugs can be released when temperature rises in the joint cavity during exercise or osteoarthritis. In contrast, the delivery system will be locked and the drug release process will stop when the arthritis lessens or exercise

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