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https://www.selleckchem.com/products/piperlongumine.html s demonstrated poor patency rates, higher primary patency is noted for stenting in the first two years. Coupled with low complication rates, this highlights a potential benefit of stenting as first line treatment for CVO. Allowing for overall poor quality of current studies, even this short-term improvement in primary patency may benefit haemodialysis patients. Further research with randomised control trials as well as assessment of adjuvant techniques such as drug coated stents/balloons, anticoagulant therapy and the role of intravascular ultrasound use is required. Intermittent pneumatic compression (IPC) is an established treatment option to remove tissue fluid from patients with lymphedema and chronic venous disease. The effects of IPC applied directly after varicose vein surgery performed with high volumes of tumescent local anesthesia have not been investigated. The aim of the present study was to evaluate the use of postoperative IPC concerning its effects on the leg volume and patient comfort after surgery. We performed an investigator-initiated, single-center, open-label randomized controlled trial. A total of 186 patients indicated for saphenofemoral junction ligation and great saphenous vein or anterior accessory saphenous vein stripping or great saphenous vein redo surgery were randomly assigned 11 to the intervention or control group. The patients in the intervention group were treated with IPC at 40mm Hg for 45minutes directly after surgery. The outcome measures were the leg volume changes calculated using an optical three-dimensional scanning system (prno evidence for a benefit from IPC could be found in the present study and increased ecchymosis was found, its standard use after varicose vein surgery cannot be recommended. The present randomized controlled trial was designed to evaluate the decongestive effects of a single postoperative session of IPC and its effect on QoL, pain, and ecchymosis

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