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https://www.selleckchem.com/products/ipi-549.html The squat test is inexpensive and less time-consuming, and therefore particularly suitable for clinicians. There is a need for appropriate tests to identify developmental delays early in life. This study investigates the Test of Infant Motor Performance (TIMP) unidimensional model and its ability to explain variance in items response, hierarchic order of the items, levels of difficulty, and the extent to which the items were appropriate to distinguish different levels of function for infants in Brazil. Six hundred fifty-five infants were assessed. Families provided sociodemographic information. Appropriate items reliability (0.99), infit (mean = 0.99; SD = 0.46), outfit (mean = 1.34; SD = 1.58), and point-biserial correlations (-0.36 to 0.92) were obtained. The model explains 74.3% of the variance, and 76.2% of the items had adequate factor relationship. The TIMP measures a single construct, has items with different levels of difficulty, and is sensitive to detect differences in the performance of distinct groups for infants in Brazil. The TIMP measures a single construct, has items with different levels of difficulty, and is sensitive to detect differences in the performance of distinct groups for infants in Brazil. To create a motor growth curve based on the Test of Basic Motor Skills for Children with Down Syndrome (BMS) and estimate the age of achieving BMS milestones. A multilevel exponential model was applied to create a motor growth curve based on BMS data from 119 children with Down syndrome (DS) aged 2 months to 5 years. Logistic regression was applied to estimate the 50% probability of achieving BMS milestones. The BMS growth curve had the largest increase during infancy with smaller increases as children approached the predicted maximum score. The age at which children with DS have a 50% probability of achieving the milestone sitting was 22 months, for crawling 25 months, and for walking 38 months. The cre

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