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https://www.selleckchem.com/products/LDE225(NVP-LDE225).html The aim of the study was to report quetiapine-relieved Pisa syndrome in a patient with Parkinson disease and to discuss the pathogenesis and treatment of Pisa syndrome. We report a 74-year-old female patient with a history of Parkinson disease for 7 years. Pisa syndrome, lateral deviation of the spine and leaning to one side, appeared more than a year ago; adjusting levodopa was ineffective. After treatment with quetiapine for visual hallucinations, the patient's right side tilt was completely relieved after taking the drug for 1 month. Drug-related Pisa syndrome may be associated with the imbalance in dopamine-choline. Pisa syndrome may have similar mechanisms and treatment options to dystonia.This is the first report of quetiapine relieving Pisa syndrome in a patient with Parkinson disease. Drug-related Pisa syndrome may be associated with the imbalance in dopamine-choline. Pisa syndrome may have similar mechanisms and treatment options to dystonia.This is the first report of quetiapine relieving Pisa syndrome in a patient with Parkinson disease. Adherence to physical activity (PA) and gestational weight gain (GWG) recommendations during pregnancy has been shown to improve maternal and fetal health outcomes, including reducing the risk for chronic diseases. Limited research has evaluated the effect of meeting PA in combination with GWG recommendations on placental efficiency (Pl-E), a surrogate marker of the placenta's ability to exchange nutrients and gas based on surface area. The purpose of this study was to measure and compare Pl-E based on meeting PA and GWG recommendations. Healthy pregnant women (n = 61) wore accelerometers in their second and third trimesters to objectively measure PA. Women were classified as active or inactive at each time point based on meeting the 2019 Canadian prenatal PA guidelines. Total GWG was calculated as weight measured in the third trimester minus self-reported prepr

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