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https://www.selleckchem.com/products/arry-380-ont-380.html Objective To evaluate the level of adaptive functioning in patients with attention deficit hyperactivity disorder (ADHD). Materials and methods One hundred children and adolescents with ADHD (79 male and 21 female) were examined using M. Weiss functional impairment rating scale (WFIRS). The total score on the ADHD-DSM-IV was at least 24 and ADHD severity was rated as «Moderately ill» or «Markedly ill» on CGI-S-ADHD scale. Results Typical for ADHD difficulties with adaptive functioning in «Family», «Learning and school», «Life skills», «Social activities» domains are more pronounced in «Markedly ill» patients compared to «Moderately ill» and increase during the transition from childhood to adolescence. Comorbid disorders (oppositional defiant disorder and anxiety disorders) lead to a significant increase in adaptive functioning impairments in most domains of daily life, including «Family», «Learning and school», «Child's self concept», «Social activities» and «Risky activities». Conclusion It is necessary not only to assess core symptoms in the follow-up of patients with ADHD, but also evaluate comorbid disorders and the level of functional impairment across the main domains of daily life.Objective To study a role of executive functions in the development of organic emotionally labile (asthenic) disorder (OELD) and oppositional defiant disorder (ODD). Material and methods The study included 66 patients, aged 6 to 8 years, including 36 children with OELD and 30 children with ODD. Fatigue was assessed by parents on a 10-point digital rating scale. SNAP-IV questionnaire for evaluation of severity of behavioral disorders, the "Strengths and Difficulties Questionnaire" for assessment of emotional and behavioral disorders, the anxiety test of P. Temple, M. Dorkey and V. Amen, A.R. Luria test for auditory-speech memory and the Test of Variables of Attention (TOVA) were used. Results and conclusion A significantly gr

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