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https://www.selleckchem.com/products/acetylcysteine.html 008) and daily activities (p = 0.001), and had a higher GOLD stage of COPD when compared to patients with good adherence patients (p = 0.012). Multiple factor analysis demonstrates that independent adverse predictors of the ARMS score included the following being single (OR = 3.18), having had more than eight hospitalizations (OR = 1.18), and experiencing dysfunction in daily activities (OR = 1.79). Male gender (OR = 0.77) and longer than 21-day hospitalizations (OR = 0.93) were independent positive predictors of adherence. In conclusion, COPD patients demonstrate a low level of adherence to pharmacotherapy. Adherence is adversely affected by sociodemographic (older age, female gender, being single, and professionally inactive) and clinical factors (more frequent hospitalizations, perception of poor well-being, disordered sleep and daily functioning, and a higher GOLD stage).STUDY DESIGN Review of a prospective multicenter registry. OBJECTIVE To report the correction of the thoracic sagittal profile in Lenke 1 curves using the bilateral vertebral coplanar alignment (BVCA) maneuver. All-pedicle-screw construtcs provide satisfactory coronal correction but fail to accurately restore the frequent thoracic hypokyphosis of Lenke 1 curves. BVCA is a recently described technique focused on restoration of the normal thoracic kyphosis alignment in AIS patients. METHODS A non-consecutive series of 49 AIS patients underwent surgical correction of the deformity by only posterior pedicle screw construct. Coronal and sagittal curve correction was assessed by conventional standing X-rays at preoperative and 2-year follow-up visits. BVCA reduction maneuvers include the correction of the deformity, while descending an implantable rod within slotted tubes attached to the convex side screws. Restoration of physiologic kyphosis is achieved by spreading the distal ends of the tubes at the thoracic spine using different-sized spacer

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